158 ANNUAL, REPORT OF THE Off. Doc. 



the capsular cells, in most areas of only moderate degree, but in some areas 

 filling up the entire capsule. 



The peripheral nerves and the anterior and posterior roots show no change 

 after careful investigation. 



Microscopic study gave perfectly normal appearances in all the viscera with 

 the exception of the kidney. These sections show some congestive swelling of 

 the glomeruli and a cloudy swelling going on to marked degeneration of the 

 cells of the tubules. 



In other words, pathologic lesions typical of hydrophobia were found in a 

 case associated with parenchymatous nephritis. Neither the pericellular nor 

 perinuclear round-cell accumulation of the central nervous system nor the 

 lesions of the intervertebral ganglions are seen in cases of nephritis. 



Inoculations. — Three rabbits were subsequently inoculated from the medulla 

 of the patient, with the result that all 3 rabbits died after a period of 17 to 19 

 days, presenting typical symptoms of rabies, and subsequent sections made 

 from the nervous systems of these rabbits showed pathologic changes typical 

 of rabies and corresponding to those found in the nervous system of the 

 patient. 



The Dog. — The dog was of the small terrier type, showed no signs of rabies, 

 and is said to have been playing with some children only a short time before 

 biting the patient. The killing and cremation of the dog prevented a subsequent 

 autopsy. 



(American iVEedicine, Vol. VII, No. 6, pages 213-214.) 



I close this report with tbe earnest plea that an effort will be 

 made to have constituted or enforced the proper laws, compelling 

 the muzzling of and quarantining of dogs at all seasons of the yeav, 

 that society may thus be protected from this fatal condition, and 

 that, if possible, it be thus completely eliminated, as in many foreign 

 countries, notably Australia. 



