No. 6. DEPARTMENT OF AGRICULTURE. 299 



of the lett lung a tubercular abscess about 2.5 cm. in diameter was 

 found, and i*i tlie bottom of the lung several similar in size and char- 

 acter were seen. The bronchial glands were enlarged to twice their 

 normal size, but showed no caseation. The surface of the pericar- 

 dium was studded wi(h minute nodules. The thoracic surface of 

 the diaphragm was covered over a large portion of its surface with 

 nodules the size of a pea, some of them pedunculated. Among the 

 nodules were many shiods of fibrin, some of them 2.5 cm. in length. 

 Similar masses were seen also 04i the costal surface of the lung. The 

 liver, spleen and kidneys appeared normal. 



The horse inoculated with human culture K showed no clinical 

 evidence of injury. The first of April its respiration was twelve a 

 minute, its temperature was 1U0.5 degrees Fahrenheit. It was 

 killed on June 25, about six months and a half after inoculation. Its 

 condition was good. It had gained ninety-five pounds in weight. 

 There was considerable fat subcutaneously, and about the abdominal 

 organs. All of the abdominal organs were entirely normal, with 

 the exception of the liver, on the surface of which many fringes of 

 fibrin were found. In the thoracic cavity both pleurae were smooth 

 and shiny, except at the point of inoculation on the side right, where 

 a mass of small nodules, with fringes of fibrin were seen. At the 

 point of inoculation in the right lung was a cheesy abscess 4 cm. in 

 diameter, and incapsulated with dense fibrous tissue, the walls being 

 6 mm. thick. Otherwise, the lung was entirely normal. In the left 

 lung were three small tuberculous nodules about 12mm. in diam- 

 eter, situated near the surface, and which had undergone caseation. 

 The disease was evidently non-progressive, and was probably retro- 

 gressive. 



Goats. i — Both the goats inoculated with bovine culture H died, 

 one in twenty-two days and the other in twenty-six days, the lesions 

 being much the same in both. There was thickening of the pleurae 

 and adhesion at the point of inoculation; otherwise they were nor- 

 mal. The lungs were covered with myriads of minute tubercles 

 about 1 mm. in diameter, which gave a gritty feel to them. In the 

 substance of the lung ho tubercles could be found. The cut surfaces 

 presented a pneumonic appearance, most marked in the smaller of 

 the two animals. Scrapings from cut surfaces in any portion of the 

 lung revealed enormous numbers of tubercle bacilli. The mucus in 

 the bronchial tubes throughout the lungs also contained large nun> 

 bers of tubercle bacilli. In the larger animal the liver, spleen, kid- 

 neys, peritoneum and diapliragm were normal. The animal lost 

 eighteen pounds in weight in the twenty-two days of its life after 

 inoculation. The small^'r goat showed involvement of the abdominal 

 organs also. The omentum was studded with pearly tubercles 2 mm 

 in diameter, one of which had undergone caseation. The surface of 



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