No. 6. DEPARTMENT OF AGRICULTURE. 317 



Calf 8409, age five weeks, weight 131 pounds, was inoculated on 

 July 29, 1898, with 10 c. c. of sputum of a patie«t at the University 

 Hospital. This patient was adult male; a miuer by occupation. He 

 had been under treatment for nine months. At this period the 

 apices of both lungs were consolidated. He had a cough for two 

 years, lost flesh, and had one severe hemorrhage. He expectorated 

 a large abount of mucopurulent sputum. This calf showed an eleva- 

 tion of temperature which continued almost without intermission 

 for (hree mouths, reaching as high as 105.8 degrees Fahrenheit in 

 August and September. On November 3, 1898, it was tested with 

 tuberculin and gave a reaction. It was killed on January 9, 1899, 

 weighing 2G5 pounds, an increase in weight of 134 pounds. It was 

 in fair condition. There was a nodule in the peritoneum at the site 

 of inoculation. Iti the omentum were numerous calcareous nodules 

 the size of a hazel-nut, and one softened nodule the size of a hen's 

 egg, which contained an inspissated {)urulent material, and five 

 smaller ones of the same character. The lungs, liver and spleen 

 were normal, but on the pleural surface 'of the diaphragm there was 

 a deposit of fibrin which contained several well defined nodules. On 

 the abdominal surface of the diaphragm was a small amount of 

 grape formation. 



Calf 8049, age about four weeks, was inoculated on May IG, 1898, 

 intraperitoneally with 10 c. c. of sputum from an advanced case of 

 pulmonary tuberculosis at the University Hospital. The sputum 

 contained many bacilli. Beyond a slight cough, which was noticed 

 in July, it showed no symptoms of discomfort and grew raj)idly. It 

 was tested with tuberculin on July 30, and gave good reaction. It 

 was killed on August 1, weight 340 pounds," condition good; large 

 amount of fat. On the surface of both lungs and on the pleural sur- 

 face of the diaphragm was a fibrinous deposit. Isa the cervical lobe 

 of the right lung a few small nodules were found on section. The 

 mediastinal and bronchial glands were somewhat enlarged. The 

 omentum contained a few nodules, and one, about one inch in diam- 

 eter, which had undergone softening, the contents being rich in 

 tubercle bacilli. The spleen showed a number of nodules. About 

 one-half of the mesenteric glands were enlarged and showed cheesy 

 degeneration. An emulsion from the centre of the softened nodule 

 in the omentum and from portions of the spleen were made a-ud 20 

 c. c. injected intraperitoneally into calf 9843, four weeks old, weight 

 108 pounds, on August 2. Beyond a slight cough, noticed on Octo- 

 ber 10, the a«imal showed no ill effects from inoculation. It was 

 killed on January 10, 1899, condition good. The omentum was ad- 

 herent to the peritoneum at the point of inoculation and contained 

 some ten nodules about the size of a pea. In every other respect the 

 animal was entirely normal. 



Calf 8050. age four weeks, was inoculated on May IG, 1898, with 



