122 ANNUAL REPORT OF THE Ott. Doc. 



^rec-8 F. oo the third day, after which it fell, and ranged from 104 de- 

 ifiecg F. to 106 degrees F. until a few days before death, when it fell 

 slightly, going as low as 101.4 degrees F. on the day of death. Breath- 

 ing had become labored ten days before death, and the appetite failed 

 a week before death, which took place March 6. 



Autopsy. — Weight. 97 pounds. Condition, fair. The right lung 

 adherent to chest-wall throughout. When separated a layer of 

 tibrin containing many tubercular masses of new-growth is seen. 

 At the poiot of inoculation is an abscess cavity 4 cm. in diameter, the 

 pus containing many tubercle bacilli and a gas-forming bacillus of 

 the colon group. Both lungs were filled with a multitude of minute 

 nodules, and some areas showed extensive caseation. The medias- 

 tinal and bronchial glands v.ere very much enlarged and caseous. 



The liver, spleen, aod kidneys were normal in appearance. 



The omentum contained a very large number of discolored, red- 

 dish areas, which were thickened, hard, and of sandy feeling. 



Microscopic Examination. — The lungs are studded with minute 

 tubercles. The liver contains many small areas of necrosis. The 

 &pleen shows a number of areas of commencing necrosis. The kid- 

 neys are normal. 



Calf Xo. 45047, aged six weeks, weight 72 pounds. Inoculated 

 March 7, 1902, with an emulsion made from the lung and bronchial 

 gland of Calf Xo. 45035, 5 c. c. being injected into the right lung, 

 and 5 c. c. into the peritoneal cavity. The temperature rose to 104.8 

 degrees F. to 106 degrees F. for ten days, then fell slightly until 

 death took place, on April 1, 1902. 



Autopsy. — Weight. 65 pounds. Considerable emaciation. Both 

 lungs are studded throughout with miliary nodules. The right lung 

 is firmly attached to the chest-wall for its entire surface, and at the 

 point of inoculation is an abscess 4 cm. in diameter, which contains 

 a milky fluid pus in which are curdy masses. The pus contains many 

 tubercle bacilli and other bacteria, but no streptococci. The left 

 lung is attached to the chest-wall for a third of its surface. Over 

 the unattached surface is a layer of fibrin, 1 mm. in thickness. The 

 chest-wall corresponding to this fibrin is thickly studded witli 

 minute gray nodules. The pericardium is attached to the lung. The 

 heart shows numerous yellowish tubercles scattered over the ven- 

 tricles, as well as the auricles, and especially numerous on the au- 

 ricular appendage. They are seated in the visceral layer of the 

 pericardium. 



The bronchial and mediastinal glands are enlarged and soggy, 

 but no nodules can be found. 



The omentum contains innumerable minute pearly nodules, and 

 many red. fleshy, highly vascular new-growths. 



