290 STATE BOARD OF AGRICULTURE. 



developed. At this time Streptococcus pyogenes and B. coli communior 

 were isolated from the nteriis. The uterine discharge was of a reddish 

 brown color and fetid odor. She was given the same treatment indicated 

 above and the uterine discharges ceased but there soon developed a peri- 

 uterine abscess. She was slaughtered October 7, 1918. 



Macroscopic examination : There is an abscess containing about one 

 hundred cubic centimeters of thick creamy pus slightly to the right of 

 median line and between uterine body and rectum. The capsule wall 

 has involved the dorsal wall of vagina and uterus and ventral wall of 

 rectum so that rectum is dissected from vagina and uterine body with 

 difficulty. Externally, the left oviduct is apparently normal. The 

 ovarian end of right oviduct is involved in the abscess capsule. The left 

 ovary is covered by peritoneum and shows a few immature follicles on 

 surface. The right ovary is completely ensheathed in fibrous tissue 

 that is a continuation of the abscess capsule. There are several small 

 abscesses in the broad ligament containing a thick creamy pus, and vary- 

 ing in size up to as large as a hazelnut. 



The cervical canal is five and one-half centimeters in length, mucosa 

 apparently normal. Uterine body is two centimeters in length. Uterine 

 cavity contains no excessive exudate and mucosa is moist and glisten- 

 ing. Jt is of a grayish chocolate color but not entirely uniform ; around 

 some of the cotyledons it is apparently more vascular. The cotyledons 

 vaiy in size from three to six millimeters in diameter and those of the 

 left horn are apparently more vascular. 



Historical examination : The mucosa of the external cervix is covered 

 in places by an epithelium tT\^enty-five microns thick and four cells deep. 

 Tn other places it is covered by simple epithelium and only six microns 

 in depth. Whether this is the result of incomplete development of the 

 epithelium subsequent to cervicitis is a question. There are no other 

 epithelial defects. There is no subepithelial cellular zone. The mocosa 

 of the middle and anterior cervix is covered in places by an epithelium 

 thirty-five microns deep and consisting of four layers of cells. In other 

 places the epithelium is simple and fifteen microns deep. There are no 

 epithelial defects. In a few places there is a subepithelial zone about 

 fifty microns deep that is slightly more cellular than the deeper part of 

 the^ stroma. Otherwise there is no differentiation between a cellular 

 subepithelial zone and a deeper fibrous layer. At one point about one 

 hundred fifty microns below the surface is an area of cells about one- 

 hundred twenty-five microns in diameter. These are apparently con- 

 nective tissue cells in the transitional stage between fibroblasts and fixed 

 connective tissue cells. 



The mucosa of the uterine body varies in thickness from six-tenths to 

 one and one-half millimeters. It'is covered by a simple epithelium aver- 

 aging about fifteen microns high. Only a few mucoid cells are seen. A 

 differentiation into an outer cellular and an inner more loosely fibrous 

 layer of the stroma is not distinct. The deeper portion of the stroma is 

 more densely fibrous than is the corresponding part of the normal wall. 

 There is a conspicuous diminution in the number of uterine glands. In 

 some portions of the gland mucosa no glands are observed. The uterine 

 glands vary in diameter from twenty-five to forty microns. 



The mucosa of left horn varies in thickness from one to three milli- 

 meters, averaging a little thicker toward the middle and anterior end of 

 the horn. The epithelium is simple and averages about twenty microns 



