EXPERIMENT STATION REPORTS. 291 



high. There are no epithelial defects. The outer cellular layer of the 

 stroma is not uniform but iu places the more fibrous deeper portion ex- 

 tends to the epithelium. A few small foci of small round cells are seen 

 in the deeper portions of the stroma. These foci vary in size from one 

 hundred twentj-five to one hundred seventy-five microns in diameter. 

 They consist of cells which apparently represent an intermediate stage 

 between fibroblasts and fixed connective tissue cells. The diminution in 

 number of glands is not as marked as in the uterine body. The mucosa 

 of the right horn shows the same changes seen in the left horn. In ad- 

 dition some of the gland luminae contain a few lymphocytes and there 

 are a few local areas of edema in the stroma. 



Case 17. Red Poll heifer three years old, was bred for the first time 

 in April, 1918, and was soon turned on pasture for the summer. During 

 the first week in December, 1918, she aborted a four months' old fetus. 

 This was apparently from service in pasture during the summer. Animal 

 was killed for beef January 21, 1919. 



Macroscopic examination: Uterus not enlarged, oviducts apparently 

 normal. Left ovary contains a corpus luteum about one and one-half 

 centimeters in diameter, also one cvst-like structure one centimeter in 

 diameter and several immature follicles slightly protruding above surface. 

 Kight ovary normal. 



External cervix is two and one-half centimeters in diameter, external 

 OS is closed. There is a small quantity of a turbid slightly adhesive 

 exudate in external os. There is some hj^pertrophy of the second and 

 third transverse folds of the cervical mucosa. Uterine body is four 

 centimeters in length. Mucosa has a fairly uniform light drab color. 

 Mucosa of right horn not uniform in color. Portions of the gland mucosa 

 are of a light drab color, others dark drab, giving the gland mucosa a 

 mottled appearance. The mucosa is moist and glistening but there is 

 no excessive exudate. The cotyledons are three to six millimeters in 

 length and of uniform color. Mucosa of left horn is of a lighter and 

 more uniform color. Cultures from uterus were negative. 



Histological examination: The mucosa of the external cervix is cov- 

 ered by a simi)le epithelium fifteen to twenty-five microns high. The 

 sub-epithelial tissue is very slightly, if any, more cellular than the deeper 

 lying stroma. There is considerable mucus between the folds of mucous 

 membrane and in the tube-like depressions in which are seen numerous 

 lymphocytes. The epithelial cells show considerable mucoid changes 

 but not to the same extent as is seen in case 808. It is apparent that in 

 this case (17) the nuclear changes are not the same as in case 808. Here 

 the nucleus is larger, more vesicular and more deeply stained than in 

 case 808. The questions arise : Is there a distinction between physiolog- 

 ical mucus production and that seen in the catarrhal conditions"? Are 

 the latter characterized more particularly by degenerative nuclear 

 changes? 



The mucosa of the middle cervix differs from that of the external cer- 

 vix only in that here the rugae and tubular depressions are more num- 

 erous and the stroma in places is slightly more cellular. In a few of the 

 spaces between the folds are numerous exfoliated epithelial cells. In the 

 mucosa of the anterior cervix the mucoid changes are less conspicuous and 

 the sub-eijithelial tissue is more cellular. Near the apex of some of 



