292 STATE BOARD OF AGRICULTURE. 



the nigae the fibroblasts are so inimeroiis that tlie stnuluie simulates 

 that of the cotj-letloii of the iion-itregnant uterus. 



The uiiicosa of th.e uterine ))0(ly averages abcjut one and eight-leiilhs 

 millimeter in thickness and is eoveied by an epithelium sixteen to tNventy- 

 five microns high. There' are no epithelial defects other than a few 

 lymjdiocytes are seen passing through the niembiane. There is a fairly 

 uniform cellular sub-e]»ithelial stratum averaging about three-tenths 

 millimeter in depth in which moderated numerous eosinopliiles are seen. 

 A few groups of glands are seen where the periglandular tissue consist 

 almost eiitirely of fibroblasts. The glandular epithelium in these groups 

 show no defects. 



Tlie mucosa of the right horn averages about two millimeters thick 

 and' is covered bj^ an epithelium twenty to twenty-five microns high. 



There are no epithelial defects except that in places numerous lympho- 

 cytes are seen passing through. There is a distinct sub-epithelial cellu- 

 lar zone which in jdaces show considerable blood pigment and numerous 

 small round cells and eosinoijhiles. The latter are more numerous. There 

 are a few foci averaging about one hundred microns in diameter in which 

 eosino])hiles are the predominating cells. One focus of polymorphonu- 

 clears and fibroblasts is seen. There are a few groups of glands in the 

 deeper layers of the mucous membrane which show a slight peri-glandular 

 fibrosis. There are m) defects of the glandular epithelium though in the 

 lumen of a few glands are seen numerous lymphocytes. 



The mucosa of the left horn averages about two millimeters thick and 

 is coveied by an epithelium sixteen to twenty-five microns high. There 

 is a fairly uniform sub-epithelial cellular zone averaging about two-tenths 

 milliineter deep. There are no defects of the glands although there is 

 a slight peri-glandular fibrosis in a few places. At one point involving 

 an artery with a lumen of one hundred forty microns and a wall eighty 

 microns thick there is a crescent shaped area of what appears to be 

 transitional fibroblasts that extends about one-third the distance around 

 the artery. At one point this area involves about one-half the thickness 

 of the arterial wall. At its thickest jtortion it is ninety microns and 

 gradually diminishes to a point at each end. 



Case IS is a Holstein cow five and one-half years old. She was bred for 

 the first time August 20, 19U, and calved May 21, 1915. After this she was 

 bred unsuccessfully a number of times and was treated for sterility 

 but records do not sliow nature of treatment. She was then bred January 

 27, 1916, and calved October 28, 191G. The records show the following- 

 service dates: Se])tember 17, 1917; Janu.ary 3, 1918; February 14, 1918; 

 March 10, 1918; August 8, 1918. There were no known abortions dur- 

 ing this time. The animal was slaughtered January 27, 1919. 



Macroscopic examination: Tlieie is a cyst four centimeters in lengt'i 

 and one and one-fourth centimeters in diameter jjrojecting above surface 

 of tioor of vagina ten centimeters posterior to external os, Cervical canal 

 c(»ntains a small quantity of clear, slightly adhesive exudate. The pos- 

 terior transverse fold of cervical mucosa is corisideiably enlarged in its 

 lower ])ortion. The left lateral portion of thii'd f(dd is also enlarged 

 but not to the same extent as is the i)osterior fold. IJody of uterus two 

 centimeters in length, mucosa fairly uniform in color. Mucosa of left 

 horn is of a light chocolate color though some portions show a little more 

 blood pigment than others. Cotyledons are normal in appearance. The 



