206 STATE BOARD OF AGRICULTUREi. 



lumen hut the iiiajorit}' of glands sliow no epithelial defects. Mjiny of the 

 gland tuhules show a peri-giandular fihiosis though this has not reached 

 the stage of scar tissue. A few localized areas of edema are observed in the 

 stroma. In the region of a cotj'ledon there is a distinct depression in 

 the mucosa but this does not appear to be due to cicatrization but to a 

 vitreous degeneration and obliteration of the uuderh'ing arteries. 



The mucosa of the right horn varies in thickness from three to seven 

 microns and is covered hj an eT>ithelium sixteen to twenty-five microns 

 high. In i^laces there is a small amount of exudate consisting of red 

 blood cells and leucocytes adherent to the surface of the epithelium. 

 There is also seen in places a la^-er of a granular pinkish material con- 

 taining a few leucocytes between the epithelium and sub-epithelial cell- 

 ular zone. This layer is fifteen to thirty microns thick. There are no 

 marked epithelial clefects except in places there is a separation of the 

 epithelial cells through which the granular layer above described is 

 continuous with the surface coagulum. The sub-epithelial cellular zone 

 is not uniform in depth but in places extends down into the stroma and 

 reaches the muscularis in places. There is seen here the same small round 

 cell infiltration and peri-glandular fibrosis as described in the left horn. 

 Adjacent to an arteriole forty microns in diameter is a focus of fibro- 

 blasts about one hundred microns in diameter. There is some disinte- 

 gration of the glandular epithelium and small round cell infiltration 

 observed in a few of the gland tubules. 



Case 22. Guernsey cow born August 30, 1910. First served December 



21, 1912, and calved normally October 2nd, 1913. Was again bred April 

 18, 1914, and calved normally Februarj^ 1, 1915. Was then bred March 

 16, 1915, and aborted May 30, 1915. She was successively bred August 



22, 1915; October 2G, 1915; December 10, 1915; April 2, 1916; and aborted 

 November 4, 1916. She was then bred January 12, 1917; February 2, 

 1917; February 26, 1917; March 18, 1917; April 9. 1917; May 0, 1917 and 

 November 6, 1917. Abortion was not observed between May and No- 

 vember. There is no record of the case between November 6, 1917, and 

 December 14, 1918, other than that there has been no known abortion 

 nor has the cow calved during that time. On December 14, 1918, the 

 following notes were recorded : There is some cloudy mucus around ex- 

 ternal OS. External cervix much congested, canal slightly dilated. 

 Uterus not enlarged but walls are flaccid. The cow was slaughtered on 

 February 11, 1919. 



Macroscopic examination: The external cervix is four and one-half 

 centimeters in diameter. The external os is slightly dilated and there 

 is i)resenta considerable amount of slightly cloudy adhesive exu<late. The 

 cervical canal is eight centimeters in length, mucosa of a grayish drab 

 color with a few ecchymotic areas. Body of uterus five centimeters in 

 length, mucosa of a darker drab and more uniform color than that of 

 the cervix. The mucosa of the horns similar to that of the body with a 

 few small areas apparently more vascular. Cotyledons are six milli- 

 meters ill diameter and of a yellowish gray color. There is a protruding 

 corjnis luti'iim about six millimeters in diameter in each ovary, also a 

 cysl-like structure in left ovary about one and one-half centimeters in 

 diameter, llight ovary is s])herical and two and one-half centimeters in 

 diameter. I.eft ovary is three by two centimeters in size. Cnl lures from 

 litems were nc^gativc. 



