EXPERIMENT STATION REPORTS. 297 



Histological examination: The nuicosa of the external cervix is covered 

 in some places by a stratified epithelium sixty microns deep and in 

 others the epithelium is simple and twenty-five microns high. The exu- 

 date has been washed off except between the folds of mucous membrane; 

 here it appears as a partly granular, partly stringy, pinkish mass in 

 Avhich many lymphocytes are seen. The epithelial defects are not marked 

 though in places there is some mucoid degeneration. The sub-epithelial 

 tissue is quite generally fibrous with here and there slight accumulations 

 of leucocytes. It is observed however, that in the region of the fundus 

 of the pits between the folds of mucous membrane the sub-epithelial 

 tissue is more cellular. Whether this is due to greater irritation due to 

 retarded drainage of the exudate is a question. The mucosa of the 

 middle and anterior cervix is covered by a simple epithelium twelve to 

 iwenty-five microns high. Mucoid degeneration of the epithelium is 

 marked. There are observed in the stroma a few foci of fibroblasts 

 averaging about two hundred microns in diameter. These are at an 

 average depth of five-tenths millimeter from the surface. The mucosa 

 of the uterine body is five to six millimeters in thickness and is covered 

 b}' an epithelium twenty-five to forty-five microns high apparently con- 

 sisting of four or five layers of cells in places. There are no marked 

 epithelial defects though in places numerous lymphocytes are seen in 

 the process of passing through the epithelium. The sub-ei)ithelial cellular 

 zone is not distinct but considerably more fibrous than in the normal 

 uterus. Many fibroblasts and distinct foci of fibroblasts are seen in the 

 stroma. The deeper portions of the stroma are more densely fibrous 

 than normal though the increased thickness of mucosa is parth^ due to 

 edema. There is a marked diminution in the number of glands. The 

 glands are not uniformly distributed but are completeh' absent in places ; 

 only a few of the glands show mucoid changes in the epithelium. The 

 mucosa of the left horn varies in thickness from one and six-tenths 

 to nine millimeters. In the thicker i^ortions considerable edeuia witli 

 leucocytic infiltration is observed. A difl'erentiation into an outer and 

 inner layer of the stroma is not uniform. The sub-epithelial zone is more 

 fibrous than normal with distinct cicatrization in places. The uterine 

 glands are more uniformly distributed than in the body but more mu- 

 coid changes with some disintegration of the glandular epithelium are 

 observed. The mucosa of the right horn varies in thickness from four to 

 ten millimeters and is covered by simple epithelium twenty to twenty-five 

 mici'ons high. There are no marked epithelial defects though a few 

 leucocytes are seen passing through the membrane. The stroma is not 

 uniformly difl'erentiated into two layers but there is a fibrosis of botli 

 layers. Much edema of the stroma is observed although the amount 

 varies considerably in different portions of the mucosa. Numerous 

 eosinophiles and lymphocytes are seen in the edematous areas. Scat- 

 tered through the edematous areas are seen grou])s of from one to four 

 gland tubules with occasionally an arteriole surrounded bv a fibrous 

 peri-glandular tissue. These groups whicli are irregularly shaped and 

 vary in size from one hundred twentj^ to seven hundred fifty microns in 

 their greatest diameter, stand out as islands surrounded b}- edematous 

 fluid. The glandular defects are not marked though there are slight 

 mucoid changes in the glandular ei)itlielium and the peri-glandular tissue 

 is distinctly, though not densely, thickened. Only occasionally are there 



