298 STATE BOARD OF AGRICULTURE. 



observed a few glands with atrophic epithelium and surrounded by scar 

 tissue. Here desquamated epithelium and leucocytes are observed in the 

 gland luminae. 



Case 23. Guernsey cow, past breeding record not available but it is 

 known that animal has had two or three calves and has been bred a 

 number of times since calving with failure to conceive. On January 

 20, 1919, it was recorded that the external cervix was very much con- 

 gested but no abnormalities of the uterus or ovaries could be detected 

 by rectal examination. • On the above date the cervix was swabbed with 

 Lugol's solution of iodine. Tliis animal was slauglitered March 3, 1919. 



Macroscopic examination : There is a small quantity of a rather ad- 

 hesive muco-purulent exudate in the anterior part of vagina and ex- 

 ternal OS. There is some hypertrophy of the external fold of mucous 

 membrane of the cervix in its lower right portion. The mucosa is not 

 of a uniform color but the lack of uniformity is apparently due to some 

 portions being more vascular than others. At the lower border of middle 

 transverse fold there is a fibrous tag adherent at each end to fold leav- 

 ing a small opening beneath tag. The mucosa of the anterior cervix is 

 adherent completelj^ closing cervical canal. The adliesions are not dense 

 but apparently of recent origin. This condition is probably a sequel 

 of the treatment administered' on January 20. The body of uterus is 

 five centimeters in length and the wall of body and left horn is much 

 thinner than normal and suggests the condition of pregnancy. The left 

 horn contains about one hundred twenty-five cubic centimeters of serous 

 exudate but no coagulum is present. The mucosa is of a light drab but 

 not uniform color. In some portions the vascular network is distinctly 

 seen indicating considerable thinning of the overlying mucosa. The 

 cotyledons average about three millimeters in diameter and are gray in 

 color. The wall of right horn is thicker than that of body and left horn 

 but there is some thinning of this wall. Mucosa similar to that of left 

 horn. Both oviducts are apparently normal. Right ovary spherical, 

 two and one-half centimeters in diameter, contains a cyst-like structure 

 one centimeter in diameter and several regressed corpora lutea. Left 

 ovary is oval and is four and one-half centimeters in its longest diameter 

 and contains a cyst two and one-half centimeters in diameter. Staph, 

 pyogenes aureus, and Staph, pyogenes albus were obtained from the sur- 

 face of mucous membrane and were also obtained from the deeper layers. 



Histological examination: No tissue is saved from the cervix and 

 uterine body. The Mucosa of the left horn varies in thickness from 

 thirty-six one hundredths to eight-tenths of a millimeter, (the uterine 

 wall is only two or four millimeters thick) and is covered by a simple 

 epithelium twenty-five microns high. The stroma of the mucosa is not 

 differentiated into two layers biit is more densely fibrous than normal. 

 The proportion of glands to interglandular tissue is apparently normal. 

 A few of the glands show cellular degeneration with numerous lympho- 

 cytes in- the gland luminae. Atrophy of the muscle fibers of the internal 

 muscular coat is apparent. Tlie mucosa of the right horn varies in 

 thickness from one and one-half to four millimeters and is covered by 

 an epithelium eighteen to thirty microns high. In places a few vacuoles 

 and disintegrating cells are observed in the epitlielium. The sub- 

 epithelial cellular zone is more noticeable than in the left horn. The 

 center of one cotyledon is depressed and appears to have undergone 



