EXPERIMENT STATION REPORTS. 299 



some induration to a depth of one hundred fifty microns. In anotlier 

 cotyledon there is a more deeply seated indurated area about one milli- 

 meter in diameter. Beneath this cotyledon are numerons glands with 

 atrophic epithelium. The condition of stroma varies in different parts 

 of horn. While there is a more or less uniform diffuse fibrosis of the 

 stroma the stage of fibrosis varies in different portions. In places the 

 inter-glandular tissue is largely fibrous, in others it consists very largely 

 of fibroblasts indicating an active condition. Numerous small round 

 cell foci averaging about two hundred fifty microns in diameter, are 

 seen both in the gland mucosa and region of the cotyledons. The condi- 

 tion of the glands varies considerably in different portions of the horn. 

 In places the glandular epithelium is apparently normal, in others there 

 is shrinking of the nucleus and caryorrhexis with disintegration of the 

 cytoplasm. Here numerous small round cells are seen, in the gland 

 luminae. 



In this case and the remaining three of this series, an attempt was 

 .made to stain sections from different portions of the uterus for bacteria 

 btit we were not able to successfully demonstrate their presence. In 

 some of the sections a few scattered small spherical bodies were seen but 

 these were not sufficientlY numerous to determine whether thev were 

 COCCI or chromidia. In view of the fact that cultures were obtained from 

 the deeper layers of the mucosa it is believed that our technique was im- 

 perfect or else there were such small numbers of bacteria that they 

 were not recognized. 



Case 24. Guernsey cow about five j'ears old. This cow aborted a 

 seven months old fetus in September, loil. A few days afterwards three 

 fetal hoofs were washed out of uterus. She soon made an apparent re- 

 covery and was bred persistently with failure to conceive. February 1, 

 1919, the author made an examination of the cow and recorded that 

 vagina contains no excessive exudate. There is a little enlargement of 

 the right horn, and right ovary contains a corpus luteum. Animal is 

 probably pregnant but not sufficiently advanced to make a positive 

 diagnosis. February 22, an examination by author found the animal not 

 pregnant but the clinical condition was not recorded. She was slaugh- 

 tered March 2, 1919. 



Macroscopic examination : The external os is slightly dilated. The 

 cervical canal is seven and one-half centimeters in length. There is an 

 excess of clear mucus in canal. First transverse fold of mucosa and 

 mucosa of anterior cervix shows quite a few petechial hemorrhages. 

 Uterine body two and one-half centimeters in length, mucosa of a fairly 

 uniform light drab color. Mucosa of left horn of a light drab color. 

 The cotyledons are not numerous and those that are present appear 

 as a very small slightly elevated grayish area with a depressed center. 

 Mucosa of right horn of a fairly uniform light chocolate color. Only 

 few cotyledons visible. Near posterior end of horn is a scar-like area, 

 grayish white in color, irregularly triangular in shape, two and one-half 

 centimeters in length and six millimeters at base. In the anterior end 

 of horn there are a few hemorrhagic or acutely congested areas at the 

 crest of the folds of mucous membrane; these areas average about six 

 by twelve millimeters in size. Both oviducts aj^parentl}^ normal. Left 

 ovary is three centimeters in diameter and contains a protruding corpus 

 luteum one centimeter in diameter. Right ovarj- is oval, is four centi- 



