No. 7. DEPARTMENT OF AGRICULTURE. 89 



Necropf^y. AYeight 407 pounds; good condition. The following 

 lesions of tuberculosis were found: In one of the left peribronchial 

 glands a yellow, caseous area one-tenth of an inch in diameter. In 

 the posterior mediastinal gland there is an area the size of a pea, 

 yellow in color and/qjiite calcareous, surrounded by a white, dense 

 capsule. In the middle mediastinal gland there is a similar area, 

 though much smaller, being but one-twelfth of an inch in diameter. 

 In one of the postpharyngeal glands there is a caseocalcareous area 

 one-half of an inch in diameter, surrounded bv an unusually thick, 

 dense, white, fibrous wall. The caseous collection contains man} 

 calcareous grains. There are also in this gland three other similar 

 areas, much smaller, about one-eight of an inch in diameter, and each 

 is surrounded by a dense capsule. In addition to this evidence of 

 tuberculosis it was observed that both lungs, although generally well 

 inflated, were heavy, soggy, somewhat leathery and without eles- 

 ticity. There were some small areas where the tissues were con- 

 tracted and dense. Histologicall}' these areas show numerous dense 

 bauds of connective tissue. The blood vessels are very much thick- 

 ened. In limited areas some of the smaller ones are almost obliter- 

 ated. Some of the smaller sublobules show the lung tissue to be 

 collapsed or organized. The peribronchial lymphatic tissue is in- 

 creased and the pleura is thickened. There is no caseation of evi- 

 dence of a tubercular process excepting as above noted. Guinea- 

 pigs inoculated with the caseocalcareous material from the thor- 

 oughly encapsulated lesions in the postpharyngeal glands became 

 tuberculosis. 



FIG. 3.— ROAN HEIFER (16,021). 



1902. December 19. 0.1 c.c. tuberculin; reaction. 



1903. February 2. 0.8 c.c. tuberculin: reaction to 106° F. 



1903. February 9. 0.0013 grm. human tubercle bacilli, intravenously. 



1903. February 18. 0.0026 grm. human tubercle bacilli, intravenously. 



1903. March 2. 0.0026 grm. human tubercle bacilli, intravenously. 



1903. March 21. 0.0039 grm. human tubercle bacilli, intravenously. 



1903. April 4. 0.0052 grm. human tubercle bacilli, intravenously. 



1903. April 10. 0.0052 grm. human tubercle bacilli, intravenously. 



1903. May 1. 0.0065 grm. human tubercle bacilli, intravenously. 



1904. March 29. 0.0065 grm. human tubeicle bacilli, intravenously. 

 1904. September 15. Killed. 



Fig. 3. 



Left bronchial gland. 



Necropfty. Weight 465 pounds; good condition. The evidence of 

 tuberculosis here consists in a very dense condition of the lower half 

 of the posterior flap of the anterior lobe of the left lung, which is 

 attached to the posterior lobe and to the pericardium and the dia- 

 phragm. This dense mass consists of a very thick wall of fibrouc- 

 tissue surrounding a sequestrum of lung tissue, about one and a 

 half inches in its anteroposterior and two and a half inches in its 

 vertical diameter. Above this mass the lung tissue of the anterior 



