90 



ANNUAL REPORT OF THE 



Off. Doc. 



lobe contains an excessive quantity of fibrous tissue appearing as 

 white bands between the lobules. These bauds are quite tirni and 

 are from one-eighth to one (luarter of an inch wide. The parenchyma 

 surrounded by these bands is studded with fine dots and lines ot 

 white, consisting of fibrous tissue. Above this sclerotic zone the lung 

 tissue is elastic and pink. There are nowhere nodules or caseous 

 areas, excepting in one of the left peiibronchial glands which con- 

 tains a caseocalcareous nodule the size of a pea. 



There is reason to believe that in this animal there has been an 

 extensive are of tuberculous tissue in the lower portion of the ante- 

 rior lobe of the left lung. This area appears to have become encysted 

 and the lung tissue above to have been the seat of numerous small 

 tubercles which were transformed into scar tissue and appear now 

 very much hardened and contracted. 



Second Group. T Kree cah^es'vhich received intravenous injections 

 of tuhercle hacilli alternating with repeated stilcntaneoiis injections of 

 tuberculin. 



FIG. 4.— RED-AND-WHITE HEIFER (16,015). 



1902. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1904. 

 1904. 

 1904. 

 1904. 

 1904. 

 1904. 

 1904. 



December 



February 



February 



February 



February 



February 



February 



March 



March 



March 



March 



March 



March 



March 



April 



April 



April 



April 



April 



April 



April 



April 



March 



April 



April, 



April 



April 



April 



September 



19. 



2. 



9. 

 15. 

 18. 

 22. 

 24. 



4. 



6. 

 11. 

 14. 

 21. 

 27. 

 29. 



5. 



8. 

 10. 

 16. 

 18. 

 23. 

 27. 

 30. 

 29. 



1. 



3. 



8. 

 11. 

 15. 

 15. 



0.1 c.c. tuberculin 

 0.8 c.c. tuberculin 

 1.0 c.c. tuberculin 

 1.5 c.c. tuberculin 

 0.0026 grm. human 

 1.0 c.c. tuberculin 

 1.5 c.c. tuberculin 

 2.0 c.c. tuberculin 

 2.5 c.c. tuberculin 

 3.0 c.c. tuberculin 

 3.5 c.c. tuberculin 

 0.0039 grm. human 

 1.0 c.c. tuberculin 

 1.5 c.c. tuberculin 

 2.0 c.c. tuberculin 

 2.5 c.c. tuberculin 

 3.0 c.c. tuberculin 

 3.5 c.c. tuberculin 

 0.0052 grm. human 

 0.5 c.c. tuberculin; 

 1.0 c.c. tuberculin; 

 2.0 c.c. tuberculin; 

 0.0065 grm. human 

 1.0 c.c. tuberculin; 



tuberculin; 



tuberculin; 



tuberculin; 



tuberculin; 



2.0 

 3.0 

 4.0 

 5.0 



c.c. 

 c.c. 

 c.c. 

 c.c. 

 Killed. 



reation. 



reaction 



reaction 



reaction 



tubercle 



reaction 



reaction 



reaction 



reaction 



reaction 



reaction 



tubercle 



reaction 



reaction 



reaction 



reaction 



reaction 



reaction 



tubercle 



reaction 



reaction 



reaction 



tubercle 



reaction 



reaction 



reaction 



reaction 



reaction 



to 105 

 to 102 

 to 103 

 bacilli 

 to 103. 

 to 102. 

 to 104. 

 to 102. 

 to 103. 

 to 103. 

 bacilli 

 to 103. 

 to 103. 

 to 102. 

 to 102. 

 to 104. 

 to 103. 

 bacilli 

 to 104. 

 to 102. 

 to 103. 

 bacilli 

 to 102. 

 to 103. 

 to 102. 

 to 102. 

 to 103. 



8° F. 



8° Fi 



0° F. 



, intravenously. 



0= F. 



6" F. 



6° F. 



8° F. 



0° F. 



0° F; 



, intravenously. 



2° F. 



0° F. 



6" F. 



2° F. 



0° F. 



6-^ F. 



, intravenously. 



6^ F. 



6° F. 



6" F. 



, intravenously. 



8°F. 



3° Fl 



4° F. 



9° F. 



8° F. 



Fig. 4. 



Left bronchial gland. 



Necropsy : Weight 566 ppunds; good condition. The only evidence 

 of tuberculosis in this animal in a calcareous nodule one-eight of 

 an inch in diameter situated in one of the left peribronchial glands. 



