JMo. 7. 



DEPARTMENT OF AGRICULTURE. 



91 



This nodule is sharply differentiated from the surrounding adjacent, 

 quite normal glandular tissue, and has the appearance of a com- 

 pletely closed process. Guinea-pigs inoculated with an emulsion of 

 this nodule developed tuberculosis. 



FIG. 5.— RED-AND-WHITE HEIFER (16,019). 



1902. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1903. 

 1904. 

 1904. 

 1904. 

 1904. 

 1904. 

 1904. 

 1904. 



December 



February 



February 



February 



February 



February 



February 



March 



March 



Ma.rch 



March 



March 



March 



March 



April 



April 



April 



April 



April 



April 



April 



April 



March 



April 



April 



April 



April 



April 



19. 



2. 



9. 

 15. 

 18. 

 22. 

 24. 



4. 



6. 

 11. 

 14. 

 21. 

 27. 

 29. 



5. 



8. 

 10. 

 16. 

 18. 

 23. 

 27. 

 SO. 

 29. 



1. 



4. 



8. 

 11. 

 15. 



0.1 c.c. tuberculin 

 O.S c.c. tuberculin 

 1.0 c.c. tuberculin 

 1.5 c.c. tuberculin 

 0.0026 grm. human 

 1.0 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 0.0039 grm. human 

 1.0 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 0.0052 grm. human 

 0.5 c.c. tuberculin 

 1.0 c.c. tuberculin 

 2.0 c.c. tuberculin 

 0.0065 grm. human 

 1.0 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 

 c.c. tuberculin 



1.5 

 2.0 

 2.0 

 3.0 

 3.5 



1.5 

 2.0 



2.5 

 3.0 

 3.5 



2.0 

 3.0 

 4.0 

 5.0 



reation. 



reaction 



reaction 



reaction 



tubercle 



reaction 



reaction 



reaction 



reaction 



reaction 



reaction 



tubercle 



reaction 



reaction 



reaction 



reaction 



reaction 



reaction 



tubercle 



reaction 



reaction 



reaction 



tubercle 



reaction 



reaction 



reaction 



reaction 



reaction 



to 105.6° F. 



to 103.4° F. 



to 102.8° F. 



bacilli, intravenously. 



to 104.0° F. 



to 103.8° F. 



to 103.8° F. 



to 103.2° F. 



to 104.2° F. 



to 103.8° F. 



bacilli, intravenously. 



to 104.6° F. 



to 102.6° F. 



to 102.8° F. 



to 103.2° F. 



to 102.6° F. 



to 103.0° F. 



bacilli, intravenously. 



to 102.8° F. 



to 102.4° F. 



to 103.8° F. 



bacilli, intravenously. 



to 102.9° F. 



to 103.0° F. 



to 103.0° Fi 



to 103.8° F. 



to 102.4° F. 



September 15. Killed. 



Fid. 5. 



Left bronchial gland. 



Necrop^ ■ '. AVeight 580 pounds; good condition. One of the left 

 peribronchial glands contained two nodules, each about one-tenth 

 of an inch in diameter. Both are distinctly calcareous and are 

 sharjjly differentiated from the immediately adjacent, quite nor 

 mal gland tissue. 



The right lung is rather dense and leathery and contains some 

 collapsed areas. In such a collapsed area there is found an infiltra- 

 tion of round cells surrounding the bronchial walls. The lymphatic 

 nodes in the same region are greatly increased. The alevoli are 

 oedematous and in some places the exudate has undergone organiza- 

 tion. 



There is no evidence of caseation or of tuberculosis in the lungs or 

 elsewhere, excepting as noted in the left peribronchial gland. 



