No. 7. 



DEPARTMENT OF, AGRICULTURE. 



96 



Necropsy : Weight 313 pounds; very poor condition. This heifer 

 was Ivilled because it was in such bad condition that it could not 

 live long. 



The clostal pleurae of both sides are coated with masses of round 

 and flattened nodules occurring singly and in patches. The largest 

 patch is nearly a foot in diameter and about two inches thick. Both 

 lungs are covered with round and flattened nodules, some of which 

 are closely attached to the pleura and some of which hang from the 

 pleura singly and inclusters. There is a fringe around the borders 

 of the lungs about two inches wide and very thickly studded with 

 hard nodules, the centres of which have undergone caseation. Both 

 lungs contain a large number of caseous areas. The bronchial and 

 mediastinal lymphatic glands are considerably enlarged and caseous. 

 The postpharyngeal glands are in similar condition. The omentum, 

 the walls of the stomachs, the abdominal walls, the spleen and liver 

 are coated with nodular masses that are characteristic of pearl dis- 

 ease. There are numerous caseous areas in the substance of the 

 liver. The bronchial lymphatic glands are enlarged to several times 

 their natural size and are caseous. 



This is a case of "pearl disease" in the most advanced form and of 

 widest distribution. 



FIG. 12.— RED- AND- WHITE BULL (16,024.) 



1902. December 19. 0.1 c.c. tuberculin; reaction. 



1903. February 2. O.S c.c. tuberculin; reaction to 106° F, 



1904. September 17. Killed. 



Right lung. 

 Right bronchial 



Fig. 12. 



'land. 



Necropsy : Weight, 524 pounds; good condition. The right bron- 

 chial gland is somewhat enlarged and contains a calcareous nodule. 

 In the anterior lobe of the right lung there are numerous nodules 

 containing pus. These are surrounded by firm, fibrous walls. The 

 intervening lung tissue is collapsed. 



The observations here recorded show a decided difference between 

 the lot of six young cattle that were treated and the six that were 

 not treated. Since the two lots of animals were in all respects as 

 nearly equal as possible at the beginning of the experiment, and 

 since they were cared for all together and in precisely the same way, 

 excepting in respect to specific treatment, it is but fair to conclude 

 that the six treated animals were favorably influenced by the treat- 

 ment. 



We believe that we have sufficient evidence to justify the state- 

 ment that the treatment to which six of the animals were subjected 

 had the effect not only of keeping in check the progress of the tuber- 

 culosis process, but in causing a distinct and in some cases (Nos. 

 2, 3 and 6) a great retrogression of the lesions. In other words, the 

 treatment had a distinct curative effect. 



