No. 7. DEPARTMENT OF AGRICULTURE. 179 



small calcareous lesions could be found. These were well encysted 

 with a thick, hard, grayish, fibrous wall. The best results were ob- 

 tained in those animals in which the initial lesion was small and in- 

 active at the time the treatment was begun. 



In conclusion, it is my belief where a herd that contains valuable 

 animals, both for breeding and dairy i>urposes, and in which there 

 is over 8 per cent, of tuberculosis, the disease can be most easily and 

 economically eliminated by applying the tuberculin test every six 

 months combined with the use of tuberculosis vaccine and the Bang 

 system, for reactors from which it is desired to save the offspring. 



The use of tuberculosis vaccine has not as yet reached a practical 

 stage and must remain in the hands of laboratory workers until more 

 knowledge is obtained uj>on anaphylaxis, duration of immunity and 

 the tuberculin test upon vaccinated animals. 



To free a herd from tuberculosis it is necessary to have a quaran- 

 tine barn for all newly purchased animals and to keep the same 

 therein for a period of not less than three months before placing 

 them with the main milking herd. 



Before closing, I desire to acknowledge the valuable suggestions 

 and advice given me by Dr. Leonard Pearson, who at all times was 

 willing to assist me in every way possible. Further, I desire to ex- 

 press my thanks to Dr. E. S. Deubler and to Dr. E. L. Cornman for 

 general assistance in making the tuberculin tests and the vaccinations 

 of the young calves. T beg to acknowledge much assistance rendered 

 me by Dr. F. A. Mackie and Dr. W. L. Moss in postmortem examina- 

 tions. I am also greatly indebted to the owner for his ready co- 

 operation with all suggestions given, without which it would have 

 been impossible to have continued this work. 



During the year, the following well written paper was prepared 

 by Dr. John Reichel, Chief of the Laboratory. It deals with the 

 subject of rabies, which, at this time, is one of great importance to 

 every one within the Commonwealth of Pennsylvania. It is written, 

 in such a manner that it can be understood by both the layman and 

 scientific man, and gives valuable advice upon this subject: 



TMb: DIAi^NOHlS OF 1^\P.[ES 



By JOHN REICHEL, V. M. P.. f'Uicf ,if tho LalMiratoiy of thp I'onasjivania Livestock 



Saultary Boarrt. 



INTRODUCTION 



The terms rabies, lyssa, canine madness or hydrophobia, are ap- 

 plied to a specific disease to Avhich all warm blooded animals are 

 more or less susceptible. All of the terms, except hydrophobia, are 

 appropriately applied to the disease in dogs and ihe lower animals 

 in which the sum total of the usual symptoms at time is an expres- 

 sion of rage, madness or rabid condition. The dread of water as a 



