368 Toxicity of Dilute Solutions of Phenolic Compounds[A'pn\-]\i\y. 



sionally to reduce pigmentation. In most cases a marked increase in 

 pigmentation occurred when the embryos were kept in sol. of ty- 

 rosin of 0.01-0.04 percent conc. during and after the onset of pig- 

 mentation. 



9. Tyrosol, in conc. as great as 0.05 percent, retarded growth 

 and pigmentation, and killed Spelerpes larvae within 15 days. 

 Weaker sol. retarded growth and pigmentation but did not prove 

 fatal, and in time the animals developed the usual amount of 

 pigment. 



IV. LITERATURE CITED 



Banta, A. M. and Gortner, Ross Aiken. [1913 (a).] Induced 



modifications in pigment development in Spelerpes larvae. Ohio 



Naturalist; 13, 49. 

 . [191 3 (b).] Certain observations on the occurrence of 



tyrosinase in amphibian egg jell. Proc. Soc. Exper. Biol. Med.; 



10, 191. 

 Ehrlich, Felix. (191 i). Über die Vergärung des Tyrosins zu p- 



oxyphenyl-äthylalkohol (Tyrosol). Ber. d. deut. ehem. Ges.; 44, 



139- 

 Gortner, Ross Aiken. [1911 (a).] On Melanin. Biochem. Bull.; 



I, 207. 



. [1911 (b).] Studies on Melanin. IIL The inhibitory action 



of certain phenolic substances upon tyrosinase. (A Suggestion as 

 to the cause of dominant and recessive whites.) Jour. Biol. 

 ehem.; 10, 113. 



. [1911 (c).] Studies on Melanin. IV. The origin of the 



pigment and the color pattern in the elytra of the Colorado potato 

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743. 

 King, Helen Dean. (1912.) The effects of some amido-acids on 



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Biol. Bull.; 22, 273. 

 Mathews, A. P. (1909.) The influence of some amino acids on the 



development of echinoderms. Biol. Bull.; 16, 44. 

 Schreiner, Oswald and Skinner, J. J. (1910.) Some effects of 



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U. S. Dept. of Agriculture. 



