4i8 



Fasting Studies 



[April-July 



This Observation is right in line with previous observations made in 

 cur laboratory in connection with repeated fasting. These observa- 

 tions demonstrated increased resistance; a less rapid loss in body 

 weight; a lowering of protein cataboHsm; and a general physicaland 

 mental improvement (3, 8). 



TABLE I 



Data pertaining to a fast of 117 days duration 



Days 



Average daily 



urine volume 



in c.c. 



Potassium permanganate 

 Solution used in titrating 

 40 c.c. of clarified sample 



Total potassium perman- 



ganate Solution used for 24 



hr. average urine volume 



Indican Output 



per day ex- 

 pressed in mg. 



Normal period (6 days) : 700 c.c. of water per day 



Fasting period (117 days): 700 c.c. of water per day 



Water Ingestion: 2,100 c.c. per day 



SuMMARY. The course of intestinal putrefaction, as measured 

 by the urinary indican excretion, was followed in two experiments 

 upon the fasting dog Oscar. The initial fast was one of 117 days 

 in length, and the indican output was continuous and fairly high 



