1914] Frank L. Haley 443 



showed no poisonous effect after the administration of the nitro- 

 samine, but gained in weight. A spectroscopic examination of the 

 blood showed no deviation from normal. 



Three months after the administration of the nitrite sol. was 

 begun, all the animals were autopsied. The findings showed that 

 all were normal. 



The results of these experiments convince us that the use of 

 bleached flour is not detrimental to health. Although nitrite is 

 present, due to the bleaching process, it is not sufficient in quantity 

 to cause the formation of methemoglobin or the replacement of 

 normal oxyhemoglobin. We have found no pathological conditions 

 in our experimental animals arising from the administration of 

 nitrite, even with doses that were much greater than the quantities 

 of nitrite present in the flour. 



To Dr. Victor C. Vaughan I wish to express my gratitude for 

 the valuable suggestions and assistance extended to me. 



Department of Chemistry, 

 School of Mediane, 



University of Alabama, Mobile. 



