380 Biochcmisfry in New York City [Mar. 



hygienic conditions of the communities in which they lived, but 

 they contributed little towards the advancement of the science that 

 interests us so much, namely physiological chemistry. At the time 

 when Chandler, Draper and Doremus occupied important chairs of 

 chemistry in New York City, there were men like Hoppe-Seyler, 

 Baumann, Salkowski, Voit, Pettenkoffer, Drechsel, Hofmeister, 

 Kühne, Pflüger, Wurtz, and many others working abroad, who 

 directly or indirectly were influenced by the great Liebig, and his 

 great biochemical researches, and the laboratories organized by these 

 men are at the present time the chief fountains of biochemical 

 knowledge. 



At this time I wish to pay tribute to the scientific work of one 

 who was Professor of physiology at the Bellevue Hospital Medical 

 College until 1898 and then accepted the chair of physiology at the 

 Cornell Medical School, which position he occupied until 1908, 

 namely, Dr. Austin Flint. Since 1855 ^^ has published sixty-three 

 papers and essays on various medical and biochemical topics, among 

 which I wish to call your attention to a paper entitled " The influence 

 of the excessive and prolonged muscular exercise on the elimination 

 of effete matters by the kidneys," published in the New York Medical 

 Journal in 1870 and republished in an extended form in the Journal 

 of Anatomy and Physiology in 1877. These observations were 

 made on the pedestrian Weston and form the first investigation on 

 the influence of exercise upon the excretion of nitrogen by compar- 

 ing the nitrogen eliminated with the nitrogen of the food. Another 

 paper of interest, published in 1862, is one on stercorin, a derivative 

 of cholesterol, formed in the intestine and rediscovered by Bond- 

 zynski and Humnicke in 1896 and called ko prost erin by them. 

 Among others of interest I find one, " On the organic nitrogenous 

 principles of the body, with a new method for their estimation in 

 the blood," published in 1863; experiments undertaken for the pur- 

 pose of reconciling some of the discordant observations on the 

 glycogenic function of the liver in 1869; various papers on the 

 nerves and their action; treatment of diabetes, etc., etc. Not only 

 was he an enthusiastic experimenter but a very forceful teacher. 



With this short review of the past, we must, I am sure, feel 

 happy that we are living in the present, when the conditions and 



