406 En^yines as Factors in Edcma [Mar. 



coördlnations in cells, in response to various prevailing influences in 

 incipient edema?" (page 455). 



This question is vaguely general, I admit. I had in mind, espe- 

 cially, changes in the relations between enzymes and anti-enzymes, 

 increased or decreased content of inorganic radicals in the coUoids, 

 new combinations or cleavages of colloids and colloid complexes, 

 and other possible colloidal conditions connected with the inaugura- 

 tion of edema by whatever influence might be initially operative. 



I shall take occasion to return to some of these subjects and to 

 remaining points in Fischer's rejoinder, when I discuss the results 

 of various series of experiments which are now nearing completion. 



