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THE ALUMNI JOURNAL. 



At the next Alumni meeting, to be held on 

 January 15, 1896, Dr. Smith ElyJellifFe will de. 

 liver a lecture on " Our Common Poisonous and 

 Edible Mushrooms." This is a lecture which 

 everybody should attend, as it oflfers a field of 

 wide research, especially to those engaged in 

 country practice. It is a well known fact that 

 every year a number of persons die from the 

 effects of poisonous mushrcoms, having gath- 

 ered and eaten them by mistake for the edible 

 ones. It will be well worth your time to attend 

 the lecture, for it will be illustrated with colored 

 lantern slides, to impress more fully upon the 

 minds of the audience the physical properties 

 of the plants. Taken all together, the doctor's 

 pleasing personality, combined with an inter- 

 esting subject, will make it a very entertaining 

 lecture. 



IN MEMORlAfl. 



J. NIVEN HEGEMAN, 



Secretary of the College of Pharmacy of the City of 

 New York. 



Died November 11, i8gs- 



The class of '96 desire to express in 

 fitting terms their sense of the loss they 

 have sustained in the death of Mr. Hege- 

 man, the wise counsellor, the true friend, 

 the gentle mentor, the able secretary. 



Though but recently entering the paths 

 of pharmacy, which he walked so long 

 and so honorably, we realize the loss 

 which has come to our Alma Mater, to 

 pharmacy, to the community, and to his 

 family and friends. 



We desire to emulate his virtues, we 

 deplore his death, we mourn his loss. 



To our college we pledge our most 

 earnest and loyal support that the stand- 

 ard of pharmacy which he upheld be 

 ever borne aloft in integrity. 



To the family of Mr Hegeman we 

 tender our deepest sympathy and in 

 token thereof we will forward to them a 

 copy of our memorial. 



J. Y. Cantwell, 

 H. H. Hagen, 

 Jas. a. HERLI1.Y, 



Committee. 



Adopted at the special meeting of the 

 Senior Class, held at the college, Novem- 

 ber 18, 1895. 



Merton J. Coats, Pres. 



J. E- BUTTERWORTH, See. 



Eugenol Derivatives. — According to Gass- 

 man and Krafft, eugenol, the important con- 

 stituent of oil of cloves, when treated with 

 monochloracetic acid yields eugenol-acetic acid. 

 65 grs. of eugenol are heated in a sand bath for 

 20 hours with 130 grs. of 30 per cent, soda solu- 

 tion and 37.5 grs. of monochloracetic acid. The 

 sodium salt thus formed is decomposed by 

 hydrochloric acid, and the free eugenol-acetic 

 acid separates in crystals. These are volatile 

 with steam and form needles, melting at 75°, 

 easily soluble in the usually organic solvents, 

 but not easily in water. By treatment with 

 large excess of soda in amyl alcohol it is con- 

 verted into the isomeric form, isoeugenol-acetic 

 acid. This, in its turn, is oxidized by potas- 

 sium permanganate, and yields aldehyde and 

 vanillin acetic acid identical with the acid 

 formerly described under this name. It forms 

 white crystals, melting at i88°-i90°, soluble in 

 warm water and alcohol. It forms stable salts. 

 By the action of phosphorous pentachloride, it 

 is decomposed with the formation of vanillin. 

 The connection between the three acids and 

 vanillin is shown as follows: 



Eugenol acetic acid, 

 CgH, (CH..XH:CH2) (OCH3) (OCHoCOOH). 



Iso-eugenol acetic acid, 



C6H3(CH;CH.CH3) (OCH3) (OCHOCOOH). 



Vanillin acetic acid, 



CgH^lCOH) (OCH3) (OCH2COOH). 



Vanillin, 



CeH3(COH) (OCH3)(OH). 



— Berichte. 



An Isocinchonine Derivative. — Viol has pre- 

 pared the hydrobromate of isobutyl-cinchonine 

 by the following method: 14 gr. of cinchonine, 

 8 gr. of isobutyl bromide and 42 gr. of isobutyl 

 alcohol are heated for 36 hours in a reflux con- 

 denser. The crystalline salt contains one mole- 

 cule of water, which is driven off" at 100°. The 

 water free hydrobromate melts at 176°, is solu- 

 ble in water and alcohol, insoluble in ether and 

 chloroform. It is dextro rotary (a)d=-(-i25° 

 in aqueous solution.— ybwr. Pharm. a. Chem. 



Aceiamido-Antipyrin. — If antipyrin be treat- 

 ed with nitric acid, it is converted into nitro- 

 antipyrin, which, under the reducing action of 

 zinc and acetic acid becomes amido-antipyrin. 

 The latter body, when warmed with sodium 

 acetate and acetic anhydride, yields acetamido- 

 antipyrin in the form of small crystals, melting 

 at 109° C, soluble in water and in alcohol. 

 The antipyretic action of this body is very 

 marked. — Pharm. Central. 



