BUREAU OF ANIMAL, INDUSTEY, 251 



kiloOTam of body weight) were inconclusive, as such doses caused 

 vomiting. However, experiments with therapeutic doses showed 

 that carbon tetrachlorid administered simultaneously with Epsom 

 salt maintained its anthelmintic efficacy against hookworms. Seven 

 thousand persons have been given the simultaneous treatment in Fiji, 

 and apparently this method of treatment prevents even the transient 

 headache formerly noted. This being the case, it appears probable 

 that the simultaneous administration of Epsom salt with carbon 

 tetrachlorid will serve to prevent many, if not all, of the accidents 

 which follow in those cases where patients exhibit a high degree of 

 intolerance for carbon tetrachlorid administered without purgation 

 or followed by purgation. 



Critical tests of arecolin hydrobromid as a drug for removing tape- 

 worms from dogs show that this drug will remove all the tapeworms 

 present in the majority of animals treated, but that in some cases it 

 will remove only part of the worms and in other cases will fail to 

 remove any. 



Tests of various anthelmintics injected by rectum into poultry 

 showed that the small cecum worm, a difficult worm to remove with 

 anthelmintics administered by the mouth, could be removed by these 

 injections, 90 per cent of the worms coming away after an injection 

 of 0.1 cubic centimeter of oil of chenopodium in 5 cubic centimeters 

 of a bland oil in the case of birds weighing 1.5 pounds each. 



Tests of the intravenous injection of carbon tetrachlorid, of tartar 

 emetic, and of novarsenobenzol indicated that these drugs as admin- 

 istered were ineffective in destroying the agamic forms of Strongylus 

 vulgaris^ the worm which causes verminous aneurisms in horses. 



MISCELLANEOUS INVESTIGATIONS ON ANIMAL PARASITES. 



An experiment in parasitic infestation of dogs before birth was 

 carried out by feeding eggs of a dog ascarid, Belascaris marginata^ 

 to a pregnant bitch. The pups were examined the day they were 

 born and the following day, and larval ascarids were found in the 

 liver and lungs. This work throws additional light on the occur- 

 rence of ascarids in pups and shows the necessity for additional pre- 

 cautions in raising dogs free from worms. 



Studies of the toxic effect of Ascaris fluid on man were carried 

 out and pronounced ill effects of a pseudo-anaphjdactic nature were 

 demonstrated. 



Additional work on strongyles of the horse and of related animals 

 has been carried out from a systematic standpoint and with a view 

 to determining something in regard to the life histories. A new 

 species of strongyle from the zebra has been found and described 

 in a paper now in manuscript. 



The work on the life history of tapeworms of sheep has been con- 

 tinued and some results have been obtained which promise to throw 

 some light on this subject. 



During the year 724 fecal samples from imported sheep dogs were 

 examined for parasites that might be injurious to livestock. Of 

 these, 58 dogs were found to be infested with tapeworms of the genus 

 Taenia and were subjected to anthelmintic treatment before release 

 from quarantine. 



