lyS Proceedings Columbia Biochemical Association [Sept. 



C. Siilfocyanate is excreted in the urine and feces. Its elimina- 

 tion in the urine is not dependent upon the amount in the saliva. 

 Althoiigh dog saliva is apparently always free from sulfocyanate, 

 dog urine invariably contains it. The ingestion of amino acids 

 (alanin) and of nitriles (acetonitrile) increases the amount of sul- 

 focyanate in the body, as well as in the excreta. Sulfocyanate seems 

 to be produced in the body from protein. Results with a fasting 

 dog harmonize with this conclusion. The ingestion of sulfur, so- 

 dium Sulfid, thioacetic acid, thiourea and taurin did not increase the 

 Output of sulfocyanate. 



D. Potassium sulfocyanate is toxic to both plants and animals. 

 Its toxicity is so marked that indiscriminate dispensation of the sub- 

 stance to people is dangerous. The growth of molds is enhanced 

 by potassium sulfocyanate. Yeast fermentation is not affected or 

 is stimulated by moderate proportions of potassium sulfocyanate. 

 Biological proportions of potassium sulfocyanate have no inhibiting 

 influence on the growth of bacteria. The souring of milk is inhib- 

 ited by large proportions of sulfocyanate. 



28. The chemical Constitution of renal calculi. Max Kahn. 

 Sixteen stones of nephric origin were analysed according to the 

 method of Mackarell, Moore and Thomas. ^^ Most of the stones 

 were composed mainly of salts of calcium. All of the stones -con- 

 tained uric acid or urates in varying amounts, but no stone was 

 wholly composed of urates. The shape, color and consistency of a 

 stone are not criteria of its chemical composition. Three gouty 

 tophi were examined by the murexid test for urates. A negative 

 response was obtained in each case, showing that not all gouty 

 deposits are composed of uric acid salts. 



29. The colloidal nitrogen in urine from a dog with a tumor 

 of the breast. Max Kahn and Jacob Rosenbloom. (Published 

 in füll in this issue of the Biochemical Bulletin ).2^ 



30. A non-protein, colloidal, nitrogenous substance in milk. 

 Max Kahn and Frederic G. Goodridge. Since the figure ob- 

 tained for " total " nitrogen in milk exceeds the sum of the values 

 for the known nitrogenous constituents, unknown nitrogenous sub- 



^ Mackarell, Moore and Thomas : Bio-Chemical Journal, 1910, iv, p. 179. 

 ^ Kahn and Rosenbloom : Biochemical Bulletin, 1912, ii, p. 87. 



