292 Proceedings Columbia Biochcmical Association [Jan. 



by cold nitric acid Solution. Histon from fresh testes is in course 

 of prqjaration for comparisons with the product from cold storage 

 material. We lare also investigating the presence of histon in 

 flounder roe. 



55. A quantitative study of certain enzymes of the övary, 

 Uterus, and bladder, of pregnant and non-pregnant sheep. 

 Thuisco A. Erpf-Lefkovics and Jacob Rosenbloom. Published 

 in füll in this issue of the Biochemical Bulletin, page 233. See 

 abstract 53. 



56. Pathological deviations in the chemistry of uremic 

 blood.^ Nellis B. Foster. In general it was found that there is 

 a considerable increase in the amount of non-protein nitrogen in the 

 blood in severe cases of nephritis. However this is not an invariable 

 rule, as very severe cases sometimes show an approximately normal 

 figure; and a high non-protein nitrogen value has been noted in 

 other diseases, such as valvulär heart cases and pneumonia. The 

 results must be interpreted in the light of the whole clinical picture. 

 When the total non-protein nitrogen is i gram or over, per liter, 

 the prognosis is probably to be regarded as extremely grave. The 

 percentage of non-protein nitrogen that occurs as urea is extremely 

 variable, and seems to bear no constant relation to the total non- 

 protein nitrogen. The data are so lacking in concordance that it 

 must be left to further investigation, now in progress, to disclose in 

 uremic blood chemical substances which either qualitatively or 

 quantitatively present a constant divergence from normal. 



57. Effect of phlorhizin on a dog with Eck fistula. Nellis 

 B, Foster. It has been stated by Rosenfeld that the administration 

 of phlorhizin to dogs with Eck fistula does not induce glucosuria. 

 Such a result would have so much bearing upon our ideas of the 

 mode of action of phlorhizin that the matter required further study. 

 One gram of phlorhizin in olive oil emulsion was given to a dog with 

 an Eck fistula. Glucose was found in the urine, in considerable 

 quantity, for nine days subsequent to the phlorhizin administration. 



58. The relation of uricolysis to suboxidation.^*' Frederic 

 G. Goodridge and Nellis B. Foster. In order to investigate the 



'Foster: Archives of Internal Mediane, 1912, x, p. 414. 

 ^* Goodridge and Foster : Ibid., 1912, x, p. 585. 



