448 Subject Index 



Colchicine (continued) 



other than Colchicitm producing, 150 

 parts of plants yielding, 144—17 

 pharmacology of, 175-80 

 pharmacological properties, 373 

 pharmacy of, 148-53 

 physical action to explain mechanism 



of, 399-403 

 plant tumors and, 265-66 

 plants containing, 141-42 

 poisoning in man by, 175, 176, 178 

 pollen mother cells, 110 

 pollen tubes in, 107-9 

 polyploidy in plants; see Polyploidy 

 polyploidy in animals, 58-59! 380-83 

 purity, 159 



radioactiye compounds of, 196 

 recovery from effects of 



in animals, 56, 96-98 



in plants, 56, 94-96 

 regenerating liver after injection of, 



44,57 

 reversibility after, 91-98 

 singularity of, 420-22 

 solubility of, 159, 275 

 solutions of 



for animals, 373-74 



for plants, 383 

 sources of, 141-45, 150 

 specificity of reactions of, 67 

 spindle form changes, 78-81 

 technique for use in animals, in vitro 



bone marrow, 377 



duration of mitosis in, 379 



ear of mouse, 377 



eggs of Arbacia, 377 



grasshopper embryo, 377 



immature rat ovaries, 377 



mitotic counts after using, 378-80 



mitotic index, 380 



tissue cidtures, 377 

 technique for use in animals, in vivo 



adrenal cortex, 376 



Amoeba. 375 



amjjhibians, 375 



ascites tumor in mice, 376 



bone marrow, 376 



chick, 375 



cold-blooded animals, 375 



cornea of manmials, 376 



duodenum, 376 



ear of mouse, 376 



eggs, 376 



fish, 375 



gastric mucosa, 376 



genital tissues in rodents, 376 



human vagina 376 



intestinal crypts, 376 



intestine, 376 



invertebrates, 375 



lymphoid tissue, 376 



mammals, 375 



pluricellidar animals, 375 



red-cell-forming tissues, 376 



regenerating liver of rats, 376 



regenerating tissues in amphibians, 

 376 



skin, 376 



small rodents, 376 



Xenopus larval tail, 376 

 technicjue for use in plants 



buds, 384 



chromosomes, 386 



root systems, 384-85 



seed, 384 



seedling, 384 



solutions required, 383-84 

 X-ray and, 266-67 

 Colchicine-mitotic dose 

 in animals, 



cold-blooded, 96 



cold-blooded vertebrates, 97 



critical time-dose relations, 34-35 



duration of interphase, 380 



in fibroblast cidtiues, 30 



injection methods, 35 



lethality of, 96 



mitotic index a measure, 378 



period of latency, 379 



regenerating liver of rats, 44 



Siiedon. 97 



stage of mitosis and concentration of, 

 70-73 



tissue culture, 96 



Triton. 40 



Tri turns. 40 



in vitro study, 377-78 



fn vivo study, 375-77 



warm-blooded, 96 



Xenojnis. 97 

 in plants 



concentration of 0.2 '/r for poly- 

 ploidy, 383 



for repetition of c-mitosis, 55-56 



length of treatment, 56 



onion root-tip, 34, 41, 55 



pollen tubes, 37 



related to concentration, length of 

 exposures, stage, kind of cell, 38 



in Tradescantia, 33, 69 

 Colchicinetinnor, 25, 102 

 autonomy of, 104 

 cell size, 103 



growth -promoting substances, 104 

 hair cell of root, 102 

 hvpocotyl, 102 



independent of c-mitosis, 102 

 isodiamctric enlargements, 103 

 pollen tube, 102 

 region of elongation, 103 

 root, 102 

 somatic cells, 102 



