332 STATE BOARD OF AGRICULTURE. 



Tli«'r«' wtTo no tuberculous lesions found in the one killcil. It is ii diliicult matter 

 to control such experiments when it is practically imi)ossil>lo under the circumstances 

 to establish perfect isolation. Why one of these animals remained free from the 

 disease and the other succumbed to it, althouf,'!! constantly associated, is a matter of 

 s|)ecuIation. The partition walls between the two pens remained tif^lit durin<^ the 

 time, so that the tubercle bacilli must have gotten to the control pigs through some 

 other avenue. 



Microscopical examinations of the feces made occasionally usually gave positive 

 re.su Its. 



While Mysie 44 was under observation she seemed to iiave periods of improvement 

 and decline alternating with each other. 



Of Mysie 44's otlspring I have record of College Mysie 3d, vol. 37, p. 71G, dropped 

 February 13, 1831; College Mvsie 4th, vol. .3!), p. 602, dropped June 29, 1892; College 

 Mysie 5th. vol. 40, p. 753, dropped Marcli 23, 1893; College :Mysie Gth, vol. 40, p. 753, 

 dro>)pcd March 29, lSi)4, and lier last calf dropped in March, 189(1, which remained 

 unnamed and unrecorded. Of tliese ollspring only the calf unnamed is to be found in 

 the list of tuberculous animals. Their histories will be recorded in another place. 



Mysie 44th died September 5, 1897, after severe convulsions and muscular spasms. 

 Two weeks i)n'vious to her death, nervous disorders were very noticeal)le, and a week 

 before her death she sullered from an attack similar to that wliicli caused her death. 

 IJesides the convulsions, there were muscular twitching and inability to control vol- 

 untary muscular movements, and apparently considerable pain, which was evidenced 

 by marked groaning. Post-mortem examination was made with great care after her 

 death. The spinal cord and brain were removed, but no tuberculous lesions could be 

 found. In sliort, we could discover no pathological changes, either in the organs them- 

 selves or in the canal. The nervous symptoms were probably due to some changes 

 in the nervous sj'stem beyond the reach of the naked eye. The posterior pharyngeal 

 glands were normal. The lungs were decidedly tuberculous throughout. The bron- 

 chia! and mediastinal glands were badly alTected. Over the entire i)Ieura were studded 

 niuiicrous tubercles from the , smallest size which the eye could detect to the size of a 

 walnut. The oesophagus, stomachs and intestines were followed the entire length with- 

 out finding a trace of tubercle. A few of the mesenteric glands, however, were slightly 

 diseased. The liver, spleen, kidneys and ovaries were absolutely free from the disease 

 so far as our post-mortem revealed. 



In this cow, where the tubercle bacillus was constantly found in the feces, it seems 

 a little strange that the abdominal viscera were so free from the disease. 



POLY'S BLOSSOM, r,.376. 



Her sire was Orient, 2567, and dam Polyander, 2328. She was born August 21, 1892, 

 and belongs to the Guernsey breed. Her first reaction was April 1, 1896. The 

 following are the records of the tests: 



March 31. 1896, before injection, 101.1, 100.8, 101.4, 102.0, 101.0. 



April 1, 1896, after injection, 102.0, 103.2, 104.9, 103.2, 105.2, 105.6, 104.3, 100.2, 

 102.5. 



August 26, 1896, before injection, 99.7, 101.4, 101.6, 102.1. 101.6. 



August 27, 1896, after injection, 105.5, 106.7, 106.8, 106.0, 106.1, 105.8, 106.6, 

 106.9, 106.2. 



April 22, 1897, before injection, 99.6, 101.4, 100.7, 99.8, 100.4. 



April 23, 1897, after injection, 10.3.0, 103.0, 104.6, 105.5, 105.1, 103.4, 103.0, 103.0, 

 103.0. 



This cow reacted from the first and continued to react through the tnree tests. 



Previous to July 1, 1897, her milk was examined frequently, but in each case 

 inoculations proved to be negative. After July 1, 1897, her milk was examined four 

 different times with positive results. 



From the time of her response to the test, her feces were subjected to examinations 

 occasionally with negative results until July 17, 1897, at which time the examination 

 gave positive results. From October 5, 1896, to April 28, 1897, two pigs were fed 

 corn mixed with her feces without contracting tuberculosis. 



The examination of her urine always yielded negative results. 



I have record of only one calf from Poly's Blossom subjected to the tuberculin test. 

 This calf was a grade which was dropped sometime during the year 1896 and had been 

 allowed to run with the mother for several months. It was condemned April 22, 1897. 



Poly's Blossom began to run down with the beginning of the year 1897. This may be 

 shown bv her weights at different times: 



