Xo. 



DEPARTMENT OF AGRICULTURE. 



113 



"The following is a report with a summary of the facts brought 

 out, in the examination of 248 animals for rabies. 



o 

 Eh 



Dogs 



Horses 



Cows, 



Cats 



Rabbits, ... 

 Guinea piss. 

 Children, . . . 



170 

 7 

 6 

 4 



43 



15 



2 



206, or S3.1 per cent, positive diagnosis. 

 S6, or 10.6 per cent, negative diagnosis. 

 6, or 6.3 per cent, result in doubt. 



As soon as a specimen for examination was obtained, where possi- 

 ble, the following structures were taken for examination: the me- 

 dulla oblongata, examined for Babes' endothelial cell proliferation, 

 the "rabid tubercle;'' the gasserian ganglion and sympathetic gan- 

 glion, examined for Van Gehuchten and N^lis' proliferation changes, 

 and the hippocampus major and cerebellum for the presence of Ne- 

 gri bodies. A small portion of the cerebellum was saved in sterile 

 glycerine fur animal inoculation, where this was thought necessary. 



"In the examination of the 248 specimens, the diagnosis was made 

 solely upon the presence or absence of proliferation changes in 113 

 cases. In 77, both the proliferation changes and Xegri bodies were 

 sought for. The diagnosis '\vas based upon the presence or absence 

 of Negri bodies alone in 49 cases. In 9 cases neither method was of 

 value; the experimental animal inoculation method was here re- 

 sorted to. 



"The recent dttte of the discovery and the announcement of the 

 diagnostic value of the Negri bodies accounts for this method of 

 diagnosis not being used in all cases. As is shovv'u in the accom- 

 panying table, the changes in the medulla oblongata namely. Babes' 

 endothelial cell proliferation or "rabid tubercle," are not always re- 

 liable and the Van Gehuchten and N^lis endothelial cell prolife- 

 ration changes in the ganglion are at times found when rabies does 

 not exist. This accounts for the omission in examining the strtic- 

 tures where these changes are usuallv found in mauv of the more 

 recent specimens: 



"In positive cases of rabies: 



•Per cent. 



8—7—1906. 



