612 STATE BOARD OF AGRICULTURE. 



peculiar appearance. This can be illustrated best by comparing it with the 

 cut surface of pigs liver where the intra-lobular tissue is considerably swollen, 

 of a light gray color and stands above the interlobular tissue. That part 

 which corresponds to the interlobular tissue is of a darker color and near the 

 cotyledons shows what appears to be numerous petechiae. In the anterior 

 encl of the horn there is a greater amount of thick purulent exudate found 

 than in the middle portion but here there is not more than one or two table- 

 spoonfuls. The appearance of the mucosa differs from that of the middle por- 

 tion in that the part which was compared with the swollen intra-lobular tissue 

 of pigs liver appears to have contracted some and is of a steel graj^ color, and 

 the inter-lobular like portions are lighter and free from petechiae. 



The cotyledons of the left horn are of a darker color than that of the gland 

 mucosa and vary in size from three mm. to six mm. in diameter and project 

 above the surface from five to eight mm. A thin Isijer of an adhesive purulent 

 exudate is adherent to most of the cotyledons in the middle and anterior 

 portion of the horn. Upon scraping this away a few small yellowish gray 

 spots are seen on the surface which suggest necrotic foci. 



The right horn is not enlarged. The mucosa is of a light drab uniform 

 color except near the base of a few cotyledons in the middle portion where it 

 is apparently more vascular. The cotyledons are a lighter color than the 

 gland mucosa and apparently normal. There is no abnormal exudate in 

 the right horn. 



In the left ovarian ligament there is a cyst about ten mm. in diameter and 

 containing a sero-purulent exudate. The left ovary is twelve by twenty-five 

 mm. in size and contains a corpus luteum about six mm. in diameter. The 

 right ovary is ten by twenty mm. in size. 



Streptococcus viridans and Bacillus coli communis were isolated from the 

 uterus. 



Histological Examination : The epithelium of the cervical mucosa shows 

 rather marked mucoid changes. The mucosa of the uterine body varies 

 from one to five mm. in thickness. There is a superficial necrosis of the 

 mucosa varying in thickness from forty to three hundred and twenty microns. 

 This necrotic zone which is quite general appears as a pinkish granular mass 

 in which numerous leucocytes are seen. Only a few living superficial epi- 

 thelial cells are seen; in most places the epithelium is not recognizable. Be- 

 low the necrotic zone there is a distinct diffuse leucocytic infiltration of the 

 mucosa to a depth of about one half mm. In addition to this, there is a 

 marked increase in the number of leucocj^tes throughout the stroma. Nu- 

 merous budding capillaries are seen in the stroma underlying the necrotic 

 zone, beautifully illustrating the defensive and reparative activity of the 

 stroma. The glandular changes are not marked although a few leucocytes 

 and granular detritis are seen in some of the gland tubules and in places the 

 glandular epithelium has retracted from the basement membrane leaving a 

 clear zone around the epithelial fining. The mucosa of the posterior end of 

 the left horn shows a superficial necrosis only in relatively small areas and 

 where seen the necrotic zone does not extend to as great a depth as in the 

 uterine body. Over larger areas of the surface the necrosed parts have ap- 

 parently sloughed. Those portions of the mucosa not showing necrosis are 

 in places covered by epithelium, in others they are bare. In places the epi- 

 thelium is low cuboidal or squamous and does not completely cover the sur- 

 face. At other places the height of the epithelium is normal but is not con- 

 tinuous, there being spaces between many of the cells. At still other places the 



