616 STATE BOARD OF AGRICTJLTURlE. 



and glycerine, two ounces. Lugol's solution of iodine has been quite generally 

 used for a number of years in the treatment of affections of the uterus and the 

 menthol-iodine-glycerine preparation has been used quite extensively in the 

 last two or three years. This work is by no means complete but the results 

 have proved to be of such interest to the writer that it is deemed advisable to 

 publish them for the consideration of those interested in this problem. 



Case No. 1 



Clinical Condition and Treatment: The vagina contained a considerable 

 quantity of thin clear mucus as in heat. The cervix was slightly enlarged 

 with some hypertrophy of the second transverse fold. The mucosa was only 

 slightly congested and excessively moist. The uterus and ovaries were ap- 

 parently normal. One ounce of undiluted Lugol's solution of iodine was 

 injected into the uterus and the uterus gently massaged to force the solution 

 into all parts of the cavity. The cervix was then swabbed with the same 

 preparation. (This technique was followed in each case reported here). The 

 animal was slaughtered seven and one quarter hours after the treatment. 



Macroscopic Examination : There is considerable stringy fibrinous exudate 

 adherent to the external cervix. The cervical mucosa is considerably con- 

 gested except in the deeper portions of the commissures and where the mucosa 

 was protected by the overlying transverse folds. There are one or two ounces 

 of a straw colored serous exudate in the uterine cavity in which is seen two or 

 three teaspoonfuls of a coagulated fibrinous material. The mucosa of the 

 uterine body shows marked congestion but not as marked as that of the 

 cervix. The congestion diminishes toward the anterior end of the horns where 

 it is hardly noticeable. 



Histological Examination : It was not possible to obtain entirely satisfactory 

 sections of this case especially from the cervix due to an error in technique. 

 The epithelium of the mucosa of the horns is denuded in most places (appar- 

 ently mechanical), where present it varies from eight to sixteen microns in 

 height; the cells are cloudy and the nuclei poorly stained. In places there is 

 some coagulum consisting of red blood cells and a granular material adherent 

 to the surface. At a few places the epithelium is separated from the sub- 

 epithelial stroma by a thin layer of what appears to be disintegrated red 

 blood cells. The blood vessels of the stroma are more. or less engorged and 

 there is some edema of the stroma. In places quite a considerable number of 

 leucocytes are seen in the edematous areas. A few sub-epithelial hemorrhages 

 are observed. 



Case No. 2 



Clinical Condition and Treatment: Cervical secretions and mucosa ap- 

 parently normal, uterus and ovaries apparently normal. One ounce of men- 

 thol-iodine-glycerine preparation was injected into uterine cavity and an 

 effort was made to swab the cervix but on account of the smallness of the 

 canal it was not effectively done. The cow was killed six hours after treat- 

 ment. 



Macroscopic Examination: External os contains a muco-fibrinous plug. 

 Cervical mucosa is considerably congested. There are about two ounces 

 of straw colored serous exudate containing a few flakes of fibrin, in uterine 

 cavity. The mucosa is only slightly congested. 



