EXPERIMENT STATION BULLETINS. 621 



than in the normal uterine mucosa. The mucosa varies from six to eight mm. 

 in thickness. It is not conceivable that this thickening is the result of the 

 treatment administered eleven days ago. If such were the case there would 

 now be evidence of an active fibrosis. It is more probable that it is due to a 

 previous inflammation. 



Case No. 8 



Clinical Condition and Treatment: The cervical secretions were fairly 

 abundant and streaked with blood as in the beginning of menstruation. Cer- 

 vical mucosa not congested. Uterus firm, tense as if in heat. One ounce of 

 undiluted Lugol's solution of iodine was injected into uterus and the cervix 

 was swabbed with the same preparation. The animal was slaughtered eleven 

 days and six hours after treatment. 



Macroscopic Examination: Cervical mucosa is apparently normal. Near 

 the posterior end of the left horn there is an irregularly cylindrical fibrinous 

 coagulum one cm. by four cm. The mucosa at this point is roughened. 

 Externally over this lesion which appears to be traumatic is a slightly raised 

 area showing a few fibrous tags. Just below the internal os there is a 

 hematoma about two and one-half cm. in diameter, in the uterine wall. 

 The uterine mucosa is apparently normal with the exception noted above 

 and the presence of a few distinctly injected sub-epithelial blood vessels in 

 the uterine body and posterior end of left horn. 



Histological Examination: There are no alterations in the mucosa of the 

 uterine body and left horn except in proximity to the lesion described in 

 gross. Here there is a small amount of exudate adherent to the surface and 

 in places the epithelium is denuded. At places the epithehum is only six to 

 eight microns in height, possibly indicating that regeneration is not yet com- 

 plete. In the right horn, there are areas where the epithelium is only six to 

 eight microns in height. At places there is a distinct periglandular fibrosis 

 in the stroma although the periglandular tissue partakes of the nature of 

 adult connective tissue and therefore is not likely the result of the treatment 

 administered eleven days ago. 



Case No. 9 



Clinical Condition and Treatment : The cervical secretions were moderate 

 in amount, clear and adhesive as in pregnancy. No alterations of the uterus 

 could be detected clinically. One ounce of undiluted Lugol's solution of 

 iodine was injected into uterus and the cervix swabbed with the same prepa- 

 ration. The animal was slaughtered fourteen days and six hours after treat- 

 ment. 



Macroscopic Examination: Cervical secretions are clear, and fairly abun- 

 dant. The cervical mucosa is normal in appearance. The uterine mucosa is 

 of a fairly uniform grayish yellow color and is moist and glistening except for 

 a small area about three cm. in diameter near the middle portion of the right 

 horn. Here the mucosa appears to be sprinkled with a very small quantity of 

 coagulated exudate giving it a ground glass like appearance. 



Histological Examination: No alterations are observed except for a small 

 area in the right horn described in gross. Here there is observed in places, 

 epithelial buds projecting above the surface. These have been described in 

 a previous case and are interpreted as preverted or excessive regeneration of 



