\" 1 A.X gust, L920] PHAB1 .■ iGNOSl 1 1 1 



and Gr 'ill i robusta (Proteaceae). The occurrence of this compound e, in 



contrast to the inactive inositol which e e in most plants. //< 



■Iron also contains a cyanogenetic glucoside. Eloist Gerry. 



S17. Pittenger, Pattl S. Preliminary note on a new pharmaco-dynamic assay method. 

 Jour. Amer. Pharm. Assoc. 8: X 1 .):; '.):)(). 1019.— Writer states 'I i1 the goldfish method is un- 

 questionably the simplest so far proposed and can be easily carried oul by tho iecially 

 skilled in the pharmacodynamic art. A tincture of Digitalis should have a minimum lethal 

 dose of 2.85 when assayed by this method. Results of the authors experiments are recorded 

 as well as details of methods employed including a list of apparatus necessary for the experi- 

 ments. — Anion Hogstad, Jr. 



818. Pittenger, Paul S., and George E. Ewe. The standardization of Piscidia Ery- 

 thrina (Jamaica dogwood). Amer. Pharm. Jour. 91 : 575-583. Fig. 1-8. 1919. — The similarity 

 between the action of Jamaica dogwood and that of Cannabis, suggested the possibility of 

 employing similar methods of standardization. The following tentative standard 

 adopted: Fluidextract of Jamaica dogwood should be of such strength that it will produce 

 incoordination in dogs in doses of 0.55 mils per kilo weight of animal and should not produce 

 incoordination in doses less than 0.5 mils per kilo, the drug being administered by capsule 

 after fasting the animal for 12 hours. A series of experiments were conducted to assay Jamaica 

 dogwood preparations according to the piscidin content, but on account of the contamination 

 with resinous matter it was difficult to obtain the piscidin in a pure state, therefore as the 

 authors state we are without a reliable chemical means of accurate standardizing Jamaica 

 dogwood preparations, but that they can be accurately standardized by the physiological 

 assay method. — Anion Hogstad, Jr. 



819. Reens, Emma. The Coca de Java. [Javanese coca.] Bull. Sci. Pharm. 26: 497-505. 

 1919. — A detailed study of the cultivation and propagation of the coca tree is given together 

 with data on collecting the leaves, the extraction and purification of the alkaloid. The author 

 states that while in South America the leaves of E. bolivianum and E. peruvianum are alto- 

 gether used, in the East Indies and especially in Java E. spruccanum or E. novogranatense is 

 cultivated. — II. Engelhardt. 



820. Robson, W. Bay trees (Pimenta acris). Report on the Agricultural Department, 

 Montserrat, 1917-18: 17. Imperial Department of Agriculture, Barbados. 1919. — A record 

 is given of the yield of Bay leaves and oil from a plot for seven consecutive years. The result s 

 of 41 distillations during 1917 are given. From these it was found that the average Phenol 

 content was 55 per cent, being 5 per cent higher than the average for 1914-16. — J. S. Dash. 



821. Robson, W. Ajowan Plant (Carum copticum). Report on the Agricultural Depart- 

 ment, Montserrat, 1917:18: 19-22. Imperial Department of Agriculture, Barbados. 1919. — 

 Interesting cultural and distillation trials are recorded with this plant. The percentage of 

 oil in the seed was found to be 3, while the per cent Thymol in the oil is given as 40 to 45. — 

 J. S. Dash. 



822. Robson, W. American horsemint (Monarda punctata). Report on the Agricultural 

 Department, Montserrat, 1917-18: 22-23. Imperial Department of Agriculture, Barbados. 

 1919. — Small trials with this plant gave satisfactory results, the oil obtained from distillation 

 containing about 44 per cent by weight of Thymol. — J. S. Dash. 



823. Rowe, L. W. Maintaining frogs for test purposes. Jour. Amer. Pharm. Assoc. 8: 

 928-930. 1 fig. 1919.— A description with sketch of a tank for maintaining frogs for test 

 purposes. — Anton Hogstad, Jr. 



824. Rowe, L. W. Digitalis standardization. A consideration of certain methods of 

 biological assay. Jour. Amer. Pharm. Assoc. 8 : 900-912. 1919. — Experiments were performed , 

 first to determine whether any relationship exists between the results of assays by the cat 



