2 so 



"On the 14th of March I drew 2 ounces of bh)0(l, pre- 

 pared it, and inunediately inoculated T. and P.'s 2-year- 

 old Jersey cow ; a few minutes later, Sadler's 2-year-old 

 Jersey cow; about 15 minutes later Proctor's 18-month- 

 old Jersey heifer; about 30 minutes later Thurman's 2- 

 year-old Jersey bull ; about an hour later Cohen's 2-year- 

 old cow (she was in wood's pasture, and had to be 

 hunted), and about an hour later we secured Nathan's 

 4-year-old cow and 6-month-old calf and inoculated both 

 of them. (Numbered in the order named). Cows Nos. 

 3 and 2 died March 25. On that day the temperature of 

 No. 3 Avas 104 ; No. 4, 103 ; No. 5, 105. March 26, No. 3, 

 107; No. 4, 103; No. 5, 105; Nos. 6 and 7, 104. No. 3 

 was too weak to stand up long at a time. March 27, No. 

 3, 105.5; No. 4, 102.5; No. 5, 102.5; Nos. 6 and 7, 105. 

 These temperatures remainc*d this way for several days 

 and then subsided. The animals suffered loss of appe- 

 tite one or two days. The bull's temperature went up 

 again in a few^ days to 104, and No. 3 developed a swell- 

 ing under the throat and Aveeping at the eyes — these 

 conditions passed off in a few days. 



"I can not understand why Nos. 1 and 2 should have 

 died and No. 3 became so violently affected when all 

 others took the regular or normal course. Possibly the 

 severity of the fever in these three cases was due to the 

 freshness of the blood at the time they w^ere inoculated, 

 the blood being somewhat old at the time the others 

 were inoculated." 



"Very respectfully, 



"Fred G. Matthews.^^ 



The time of vear when these 9 head of cattle were in- 

 oculated was not altogether suitable — the wxather was 

 a little too warm. The best time of year for inoculation 

 is from November 1st to March 1st. Moreover, some of 



