26 



organs are normal ; spleen and liver small. Cultures from these two organs 

 remain sterile. The putrid slime from the nostrils consists microscopically 

 of slimy masses, desquamated epithelial cells, pus, erythrocytes and very 

 many spirilla. A large coccus, several B. coli and aerogenes bacilli, and the 

 roup bacillus in a few specimens, were isolated. 



Fowl No. 2. Healthy cock, about one year old. 13th Dec. '01. Was 

 kept in the same cage with fowl No. i, and the diseased chickens 1-5. 



Dec. 21. — General condition normal. At the right nostril, a small quant- 

 ity of a clear serou^ fluid is visible. 



Dec. 26. — The right nostril is entirely closed with thick grey, crusty se- 

 cretion. On taking this away, large quantities of a grey, putrid, stinking 

 slime exude from the nostril. 



From Dec. 27 to January 10 there occurred chronic nasal catarrh ; some- 

 times discharging and at other times stopping. Offensive smell from nose 

 and mouth. General condition not much altered ; appetite good. No path- 

 ological changes were observed on the mucous membranes in the eyes and 

 mouth. 



Jan. 29. — ^For eight days, the bird showed neither nasal catarrh nor any 

 other abnormal appearance. Killed by decapitation. 



Post-Mortem : Fairly well nourished carcass. In the nasal parts of the 

 right ductus lacrimalis are some small, brown spots, encased in the mucosa. 



Fowl No. 5. Large, strong, well-developed hen, about i year old. It 

 was kept in a cage with infested fowl 4 for ten days. 



Jan. 10. — ^Both nostrils are partly closed by a clear, serous slimy, fetid- 

 smelling liquid. Mucous membranes very pale. General condition and ap- 

 petite, normal. 



Jan. 14. — At the entrance to the laryn.K, and on the dorsal wall of the 

 larynx itself, a pseudo-membrane is located. It has an uneven surface, is 

 yellowish-white in color, i to 2 mm. thick, and can be removed with little 

 difficulty. The undersurface after removal begins to bleed at several spots. 



Jan. 15. — At the place where the pseudo-membrane was removed, the 

 mucous membrane is apparently normal. Discharge from the nostril almost 

 entirely stopped. 



From the T6th of January to the 4th of Alay chronic nasal catarrh of both 

 nostrils, with fluctuating severity, occurred. Often the mucous membrane in 

 the mouth had lor one or several days small pseudo-membranes. General 

 condition was abnormal during the later stages of the disease, with sleepiness, 

 diminished appetite, and all visible mucous membrane pale. Chronic anaemia 

 set in, as a secondary disease, following the roup. 



Fowls Nos. 10 and 11 were healthy hens, about one year old. They were 

 kept with the diseased chickens the second half nf the month of December 

 iQOi, and the whole month of January. 1902. General condition remained un- 

 changed. Eyes and nostrils remained normal. Several times on the mucous 

 membranes in the mouth, small croupous membranes appeared for one or two 

 days ; then they disappeared again. The mucous membrane was pale, and 

 was sometimes covered with a stickv slime. 



