35 



ocuH. It is about 1-2 mm. thick, and was removed. The mucous membrane 

 under it is grey and uneven. Several small thin membranes have appeared 

 near the tongue. 



March 27. — The membrane in the eye has reformed General condition 

 improved. 



April 2. — A solid, smooth tumor has formed in the depth of the right upper 

 eye-lid. It has extended towards the nostrils. 



April 15. — Chronic, putrid conjunctivitis. Eye-lids often sticking together. 

 Croupous membranes of the Conjunctiva always reappear after removal. Small 

 pseudo-membranes often appear in the mouth. General condition disturbed 

 ivith loss of flesh. Killed. 



Post^Mortem : Eye-lid contained gray, slimy masses. Mucous is uneven. 

 A cheesy membrane, about one cm. 2 in size and two to four mm. thick covers 

 the mucosa of the upper eye-lid. (.Fig. 9). It adheres firmly to the mucosa, 

 and is directly connected with solid, cheesy matter in the depths of the eye-lid. 

 The mucous membrane of the nares shows a few small, bloody extravasations. 

 Other organs are normal. 



Fowl No. ^7. Healthy, young hen which had had roup in the early winter. 

 Inoctdated like Fowl No. 36 in the left eye. After 24 hours, the eye-lid was 

 swollen. Later a heavy, putrid catarrh of the conjunctiva set in, and pseudo- 

 membranes formed several times on the conjunctiva. The general condition 

 was more or less disturbed, and the appetite normal. 



April II. — The posterior half of the cornea was covered with an irregular 

 pseudo-membrane, about i>2 mm. thick, yellowish-white, the other half clear, 

 with the exception of a small turbid border near the pseudo-membrane. .A.t 

 the same time, the conjunctival secretion smeVt offensively, 



April 12. — A great part of the pseudo-membrane had disappeared, leaving 

 the cornea uneven and gray. Two small membranes have formed on the up- 

 per eye-lid. At the place where the cornea had been covered by the pseudo- 

 membrane, an ulcer developed, grew deeper and deeper, and opened on the 

 17th of April into the anterior eye cavity. The lens fell prolapsed and grew 

 together with the perforated cornea. The cornea wound soon became filled 

 up with a gray granulated tumor, which regenerated slowly. 



The general condition was very much disturbed, and never again became 

 normal. 



On the ist of May, the general condition' was very bad. All visible mucous 

 membranes were very pale. The sweihng in the eve-lids and the conjunctival 

 catarrh have disappeared, but the hen was b'ind. Death o^ccuTed on the 4th 

 of Jtme. 



Post-Mortem : The Post-mortem examination showed all symptoms of 

 severe anaemia. The corpora vitrea were partly, softened, the retina split in 

 many places and portions of the retina were mixed with th.e liquefied corpus 

 vitreum. 



Fowl No. 38. Hen about two years nld. 



April 3.— Was inoculated with virulent Roup bacillus, 1-5 c.c. under the con- 

 junctiva of the right eye. and on the scratched mucous membrane of the mouth. 



