38 



and eye-lids with aliDut 1-5 c.c. O'f a bouillon culture of tlie roup bacillus, which 

 had been growing on artificial media for about two months. The only re- 

 sults were slight swelling, whicb generally disappeared after a few days. They 

 were inoculated again with the roup bacillus, wdiich had been previously passed 

 through two pigeons. Local swelling followed the iniection. with putrid, 

 chronic catarrh of the conjunctiva, and diphtheritic membranes in the mouth. 

 Tn pigeon No. 5. on the 20th day after the infection, a bad swelling, with 

 putrid catarrh of the nostrils, set in. and remained until death occurred. The 

 tumor in the left upper eye-lid trrew down towards the nostrils. The side of 

 the face became very much swollen, hot and painful. .\fter a while, the centre 

 of the tumor became solid, and the left half of the palate began to grow down 

 into the mouth cavity. At the lateral side of the palate, croupous membranes 

 appeared, and always reappeared afer removal. At other places in the mouth 

 and pharynx, similar membranes appeared. The general condition of this 

 bird was always disturbed. Tt lost most of its flesh, and died the 14th of 

 .^pr^]. (Second inoculation had taken place on the Qth of February"). 



Post-AIortcm : A putrid chronic conjunctivitis is present. The tumor on 

 the left side of the face is formed by a solid yellowish-white cheesy mass, b^- 

 ing just under the skin. This cheesy mass protrudes into the infra-orbital 

 cavity, and also fills the nasal cavities. The tumor had pressed down the 'e^t 

 part of the palate towards the mouth cavity and cause a total absorption fby 

 pressure") of the bone at the lateral edge. Here, a thick yellowish cheese- 

 like pseudo-membrane had formed, and this was in direct contact with the 

 cheesy matter in the infra-orbital cavity. The lower parts of the nasal cavity 

 contained a little putrid, slimy secretion, which liad an offensive smell. 



Tn Pigeon 6, a putrid catarrh of the nares appeared the 6th day after the 

 second infection (19th of ^larch). The left palate began to be pressed down 

 towards the mouth. On the nth day (24th of IMarch) both nostrils were en- 

 tirely closed with dried secretions, and the bird kept its beak open for breath- 

 ing. The left eye was shut, the lids sticking together. On opening the lids, 

 a putrid, slim}- secretion, containing many solid, cheesy masses, could be press- 

 ed out. The anterior part of the cornea was covered with yellowish, uneven 

 pseudo-membranes. This was removed, and the remaining cornea had th? 

 appearance of a cancer. Tt was soon covered again with a pseudo-membrane. 

 The general condition had not been very much disturbed at the beginning. 

 but grew worse towards death, which occurred the 27th of March, that is 15 

 days after the second, or 39 days after the tTrst inoculation. (See Fig. 8). 



Post-^Iortem : Carcass in poor condition. Nostrils and left eye are cov- 

 ered with dirty, offensive s^melling secretions. The left conjunctival sac con- 

 tains a slimy, putrid, lacrymal secretion, and a solid, cheesy mass. Con- 

 junctiva is gray and uneven. Only a small part of the cornea, the posterior 

 edge, has a normal appearance, the other part beng covered with a pseudo- 

 membrane, wdiich had spread upon the surrounding conjunctiva. No turbid 

 zone betw-een diseased and healthy cornea exists. Under the pseudo-mem- 

 brane, the cornea has the appearance of a cancer. A solid yellowish, cheesy 

 mass was extracted from the left upper eye-lid. There was also a little tumor 



