PUBLISHED BY THE ALUMNI ASSOCIATION 

 OF THE COLLEGE OF PHARMACY OF THE CITY OF NEW YORK. 



Vol. I. 



New York, November, 1894. 



No. 7. 



A niCROSCOPICAL AND CHEMICAL EXAHINATION OF CLOVES.* 



M 



By henry KRAEMER. 



ORE than ayear ago, a sample of a filter paper and extracted in a Soxhlet 



Li 



NE 

 BO' 

 Oi 



spice was submitted to the author, 

 an examination of which revealed the 

 presence of a large quantity of starch. 

 The question was then asked: "How 

 much is there of this adulteration ? " A 

 quantitative answer was desired without a 

 chemical analysis. This was the begin- 



apparatus by means of petrolic ether. 

 Some of the ether was recovered, and the 

 remainder was siphoned off by means of 

 a siphon and a suction of air. The oil 

 thus obtained had a viscous appearance, 

 and on the addition of alcohol about 0.16 

 per cent, of a white resinous compound 



ning of the present work, and very natur- separated, which on the filter assumed 



ally the thought arose. Isit possible to ob- the form of a very fine gauze. To this 



tain quantitative as well as qualitative filtered solution from 8 to 10 C.c. alcoholic 



results with the microscope? The results potash solution (i C.c. ^0.09856 KOH) 



are embodied in this paper — which is in- 

 tended, however, merely as a preliminary 

 paper — on the comparison of quantitative 

 microscopical with chemical examina- 

 tions, and it is hoped will reveal the 

 possibilities of research in this direction. 

 At the same time are given the results of 



were added. The alcohol was removed 

 on a water-bath, and to the nearly dried 

 mass from 2 to 2^ C.c. of benzoyl chlo- 

 ride were added. The mixture, in a flask 

 similar to that in which the extraction 

 had been done, was stirred with a glass 

 rod until the reaction was complete. 



analysis of some commercial samples of Water containing some KOH was then 



clove oil and cloves by Thoms' method added, and the whole heated on a water 



(with perhaps a slight modification) of bath for a few minutes, then removed and 



determining the eugenol in the form of a placed in ice water, and when cooled the 



benzoyl compound. 



Extraction of oil from cloves. — 10 Gm. 

 of the powder were mixed with 10 Gm. 

 of dried calicum sulphate, wrapped in 



* Read at the 42d Annual Meeting of the American 

 TPharinaceutical Ai^sociation, AsheviUe, Sept., 1894. 



clear liquid decanted, and if there were any 

 floating oily particles, these were removed 

 in a separatory funnel by means of ether. 

 This washing was continued 3 or 4 times, 

 and finally the benzoyl eugenol was 

 separated from the water by means of a 



