THE ALUMNI JOURNAL. 



89 



ties are the same as that of Loretiu (m-iodo-o- 

 oxychinolin-ana-sulphonic acid), to which it is 

 closely related. 



Gallol. — An aluminum gallate, insoluble in 

 water, forms stable solution in NH4OH. Light 

 astringent 



Crystalline Guaiacol. — The investigations of 

 Bebal have demonstrated that chemically pure 

 guaiacol is a crystalline solid of m. p. 32° c. 

 and b. p. 204° c. Obtained by exposing com- 

 mercial C. P. guaiacol (90 per cent.) to low tem- 

 perature and separating the crystalline mass. 



Lysetol — A dimethyl-piperazin. like piper- 

 azin it is a valuable solvent for uric acid. It is 

 a very soluble crystalline salt, strongly alkaline 

 yet not caustic. — Bayer & Co. Phar. Ztg., '94- 

 T16. 



Lysol. — The Therap, Mouatsheft ('94-46- 

 recommends the following : Tricresol 50 parts, 

 saponis kalina (Ph. G) 35 parts, aqua dest. 15 

 parts. Sig. 20 c. c. to the liter of distilled water 

 The amount of soap may be diminished if de- 

 sired. 



Migriinin. — ^ According to J. Hoffmann, {Phar. 

 Weekal) this consists of antipyrin 89.4 per cent. , 

 caffeine 8.2 percent., citric acid 0.2 percent., 

 and moisture 1.84 per cent. 



Neurodln. — An acetyl-p-oxy-phenylure- 

 thane.— E. Merck. 



C6H,< 



0-CO— CH3 

 NH— CO— OCH, 



Is prepared by the action of chlor-ethylformic 

 ester upon p-amidophenol. 



C CI 0,-C,H5-|-CeH,<gg^ 



CeH,< 



OH 



NH— CO— O C.,H-- -H CI 



The p-oxyphenylurethane formed is acetyl- 

 ated by heating with acetic anhydride. Forms 

 colorless odorless crystals, soluble i in 1400 of 

 cold water. Melting point 87° C. As antisep- 

 tic, in doses of 0.5 grains, it lowers the tem- 

 perature 2.5° to 3°. As anodyne in neuralgia, is 

 given in doses of i to 1.5 Gm. 



Saliiiiiin. — Aluminum salicylate, insoluble in 

 water and alcohol, soluble in alkalies; with 

 aqua ammonia it forms a neutral soluble double 

 salt ; astringent. 



Tannal. — An aluminium tannate, energetic 

 astringent, insoluble in water. Its double salt, 

 aluminum tannico-tartaricum, is on the con- 

 trary very soluble. This compound is sold by 

 Riedel in compressed tablets, as its aqueous 

 solution is not stable. 



Therrnodin — an acetyl p-althoxyphenyl ure- 

 thane.— E. Merck. 



P TT ^^OC >H-, 



^■■"^^--N— COCH,— CO— OC2H5 



In p— oxyphenyl urethane 



'NHCe 

 -OC,H 



(.f.^NHCeH,OH 



the H of the hydroxyl group is replaced by an 



ethyl group, thus 



^^^NHCeH.OC.H^ 

 ^^ --OC2H5 



This body is antipyretic but not free from side 

 effects, it is acetylated yielding thermodin. 

 This forms white needles, odorless and tasteless, 

 melts at 86° and only soluble i in 2600 of water. 

 Antipyretic dose is 0.5 Gm. 



J'litrin. — Strouchein & Co., of Berlin, offer a 

 concentrated meat extract in powder form, one 

 part of which represents the nutritive value of 

 four parts of beef. — V. C. 



OBITUARY. 



Brown-SEQUArd. — The death of the famous 

 pathologist. Dr. Brown-Sequard. took place 

 April 2, 1894. Dr. Sequard was 77 years of age, 

 having been born at Port Louis, Mauritius, on 

 April 8th, 1817. He was the son of Mr. Edward 

 Brown, of Philadelphia, United States of Amer- 

 ica, by his marriage with a French lady. Charles 

 Edward Brown-Sequard went to Paris in 1838, 

 to complete his studies, and was received as a 

 member of the medical faculty two years later. 

 From the outset he devoted himself specially to 

 researches in experimental physiology, paying 

 particular attention to the composition of the 

 blood, animal heat, and the nervous and muscu- 

 lar systems. His discoveries in these directions 

 led him to adopt special treatment in cases of 

 nervous disorders. In 1864 he went to America, 

 and was appointed profes.sor of physiology and 

 nervous pathology at Harvard University. He 

 remained in the United States for five years, 

 when he returned to France, but only for 

 a few years, going back again in 1873 to New 

 York, where he founded the Archives of Scien- 

 tific and Practical Medicine. Once more re- 

 visiting France, he was in 1878 called upon to 

 take the chair of Experimental Medicine at the 

 College de France. In 1886 he was elected a 

 member of the Academy of Science, having 

 already been decorated with the Legion of 

 Honor in 1880. The celebrity of his name, as 

 far as the general public is concerned, however, 

 dates from 1889, in which year he aroused a 

 keen controversy both in the press and in 



