88 



THE ALUMNI JOURNAL. 



Filter Paper Freed from Grease. — Schleicher 

 and Schiill. {Pharm. Centralh.. Cheml. News, 

 1894, 121). This paper is specially prepared for 

 milk analysis according to the Adams process 

 It contains but 0.025 per cent, of fatty matter, 

 whilst unprepared paper contains as much as 

 0.66 per cent. 



Canella Bark. — H. G. Greenish has examined 

 canella barks from various sources and finds 

 that the structure of the bark is by no means so 

 uniform as it has hitherto been considered. 

 Notable variations have been demonstrated, and 

 the occurrence of these variations is of import- 

 ance, inasmuch as it is precisely these barks of 

 more or less abnormal appearance that the his- 

 tologist is called upon to identify. To ignore 

 such variations is therefore to render the deter- 

 mination uncertain. Of special interest is the 

 possible presence of both schlerenchymatic cells 

 and cells with red resin, for both of these 

 elements have been regarded as especially char- 

 acteristic oi Cinnaiiiodendron corticosuin. In 

 determining the identity of barks exhibiting 

 either or both of these characters, caution must 

 therefore be exercised. The paper is well illus- 

 trated and should be consulted for detailed 

 information. — Pharm. Jour. Trans.. 1894, 793. 



NEW REMEDIES. 



Argentamin. — An antiseptic, employed in 

 gonorrhcea. It is a solution of silver phosphate 

 in aqueous solution of oethylendiamine. Iti the 

 preparation of this the Scherings have sought 

 to present an antiseptic, which does not precipi- 

 tate albumen, held in solution in a non-corrosive 

 and non-toxic solvent. It has been found that 

 the antiseptic power of strong alkaline solvents 

 is greater than simple aqueous solution, since 

 the alkalies dissolve the membrane of the 

 micro-organism — as organic bases adapted to 

 this purpose are tethylendiamine and alkyl 

 derivatives, piperaziu, etc. As antiseptics, 

 which, in conjunction with these organic bases, 

 do not precipitate albumen, are phenol, cresol, 

 thymol, napthol, guaiacol and silver salts. 

 The solutions are prepared thus, after the pat- 

 ent : 10 parts of a^thylendiamine are dissolved 

 in 500 parts of water, adding 10 parts of freshly 

 dissolved cresol. Where creosote or guaiacol 

 are employed, it is better to use a larger amount 

 of the base (asthylendiamine). For the prep- 

 aration of the silver solutions 10 parts of silver 

 phosphate (nitrate or chloride) are added slowly, 

 with constant stirring, to a solution of 10 parts 

 of the base in 100 parts of viaX^r.—Apoth. Ztg. 

 1894-211. Phar.Centralh. 1894-180. 



Bismuth Phenates — The firm of Von Heyden 

 made the discovery that those bodies belonging 

 to the group of phenols (carbolic acid, cresol, 

 napthol, pyrogallol, etc.) unite with bismuth, 

 thereby losing their toxic properties. They are 

 indifferent to the stomach, insoluble in water, 

 alcohol and ether. They are retained by re- 

 action between the alkali salts of a phenol and 

 the inorganic salts of bismuth. Among ihese 

 pyrogallol bismuth is of interest. Pyrogallol 

 itself, because of its intensely poisonous nature, 

 is not employed internally, and only externally 

 with great caution ; the bismuth compound is 

 almost non-toxic, and is a valuable antiseptic 

 in treatment of intestinal diseases — also useful 

 in skin disease. 



Von Heyden's patent salt contains 50 per cent, 

 of bismuth oxide, the formula being expressed 

 thus : 



O 



.3-(OH), 



)Bi. 



O 



(C,H3=(OH), 

 It is a yellow powder, insoluble in water and 

 alcohol, soluble in caustic soda solution (differ- 

 ent from all known bismuth salts) and hydro- 

 chloric acid. Must be free from subnitrate or 

 oxychloride of bismuth. 



Depilitant. — 'L,€\s\\V.oxi. {Monatsh. f. prak. 

 Dertnat. '94-233) recommends the well known 

 barium sulphide paste, which is prepared by 

 forming a paste of barium sulphate, charcoal, 

 sand linseed oil ; this is then heated to redness 

 for some time in a crucible, yielding a dark blue 

 barium sulfide. Then mix the following : 

 Barium Sulfide, fine powder, 10 parts. 

 Zinc Oxide, " " 5 ' 



Starch, " " 5 " 



When used it should be mixed with suffi- 

 cient water to form a soft paste, then applied to 

 . the parts ; as soon as dry (10 min.) it is washed 

 off. 



Diapthol.—O. oxychinolin — m— sulforicacid. 

 E. Merck. Chinaseptol. To a certain extent 

 diapthol is the aseptol (orthophenol sulfonic 

 acid* of the (chinolin series. 



(Ana) CH CH (gamma) 



(Para) 



HC C CH (beta) 



(Meta) SO;, HC C CH (alpha) 



(Ortho) OH N 



It forms yellowish- white crystals, insoluble 

 in water, melts at 295°. Its therapeutic proper- 



* Alumui Jour., p. 8 



