THE ALUMNI JOURNAL. 



benzene-mono-carboxylic acid. By ac- 

 tion of sulfuric, on benzoic acid, sulfo- 

 benzoic acids are formed 



(c H /-SO -0H\ 

 V ' '"^COOH / 



the amide-anhydride of the ortho-acid is 



saccharin ^ -^^ ^^SO.-. ^y^- 

 ^otl,<^^Q" J> IN hi 



Salicylic acid is tlie acid of the corre- 

 sponding salicylic aldehyde, it is an 

 ortho-oxy-benzoic acid p „ ^-OH 



The phenyl ester of this salol 



-OH 



■COO— CoH, 



If a H of the amido-group in the 

 amido-phenyl-ester of salicylic acid 



('^•'^'^CO,— CeH,— NhJ 



be replaced by an acetyl (CH3-CO) radi- 

 cal, salophen is obtained, this is an acetyl- 

 p-amido- phenol-salicylic-ester 



P TT ^^OH 



^6 ri4<^ CO— CeH.N H— CO C H3 

 The corresponding acid of the above 

 anisic aldehj^de is anisic acid, 



methyl-p-oxybenzoic acid 



C6H4 



(■ 



P TT /-"OCHj \ 



^^"^^COOH / 



its medicinal properties are very similar 

 to salicylic acid. 



We have learned that mono-oxy- 

 benzoic acid is salicylic acid; di-oxy- 

 benzoic acid is protocatechuic acid; tri- 

 oxy-benzoic acid \s gallic acid 



C6H,<;^^Pj^-^/; tannic is a di-gallic acid. 



Basic gallate ot bismuth is dermatol. 



The benzene nuclei condense, the two 

 rings so combine that they have two 

 adjoining carbon atoms, thus — 

 CH CH 



HCZ-XCXXCH 



I li lA C,„H« 



HC II CH 



x/cx/- 



CH CH 

 7iapthalene (antiseptic) is formed. 



By the replacement of H by OH group 

 alpha or beta iiapthol results, the beta 

 derivative being a valuable antiseptic. 

 The napthyl ether of salicylic acid is 

 betol, therapeutically this is closely re- 

 lated to salol, the latter being split up 

 in the intestines in salic5^1ic acid and 

 phenol, betol is likewise split up into 

 salicylic acid and napthol. 



r TT ^^^^ p XT ^^^ 



(^en,<^(^Qfj '^'■■"'^CO,— CeHg 



Salicylic Acid. Salol. 



P TT /--C^H 



^»^^^CO,— Ci„H, 



Betoi. 



lyike phenol, napthol unites with sulfuric 

 acid, the alumia salt of this is alicninol 

 an antiseptic. 



Napthol yields an oxy-acid (analogous 

 to salic3^1ic acid), alpha-oxy-napthoic acid 



OJi 

 CioH,<;qqqjj an anti.septic. 



Anthracene arises from the condensa- 

 tion of three benzene rings 



CH 

 CeH,< I >C6H, [ this on 

 CH 



oxydation yields anthraquinone 

 (CeH,<^g>C,H,) 

 Alizarine is a di-oxy-anthraquinone 



(C,H,<^^>C,H,(0H/,)) 



the introduction of a methyl group into 

 this yields chrysophanic acid, employed 

 in skin diseases. 



BASES — ALKALOIDS. 



This class of compounds comprise de- 

 rivatives and condensation products from 

 a ring similar to benzene, differing how- 

 ever in the replacement of a carbon atom 

 by that of a nitrogen, this ba.se is called 



CH 

 HC/XCH 

 Pyridin, CH^N. || | 



HC\/CH 



N 



