118 



C. U. C. 1'. ALUAlNi lOL'KXAL 



mils of ether, should not leave a weigh- 

 able residue after evaporation. A solu- 

 tion of I gramme of hexophan in lo 

 n^ils of ammonia water should be per- 

 fectly clear and transparent, nor should 

 this solution react with sulphuretted 

 hydrogen, either before or after addition 

 of diluted acetic acid. The filtrate ob- 

 tained after saturating a like ammoniacal 

 solution with diluted nitric acid, should 

 not become turbid upon addition of silver 

 nitrate or barium nitrate solution. Upon 

 complete ignition, 0.5 gramme of hex- 

 ophan should not leave a weighable 

 residue. 



If 0.5 gramme of hexophan is dis- 

 solved in 40 mils of decinormal KOH, 

 V. s., and the excess, of alkali titrated 

 with decinormal HCl, v. s , it should re- 

 Cjuire from 9.50 to 9.45 mils of the latter 

 to restore neutrality, using phenol- 

 l)hthalein as indicator. 



It is claimed to possess value in the 

 treatment of acute muscular and articnJar 

 rheumatism, lumbago, spinal myosis, 

 sciatica and other pains of nerve origin. 

 It is also used as a prophylactic in these 

 ailments. It is administered in gramme 

 doses, four times a day, later reduced to 

 three times a day. Hypodermically it is 

 given in doses of one-half gramme. For 

 the latter purpose, the sodium salt of 

 hexophan is preferred. This is soluble 

 in six parts of water, and for each 

 gramme of hexophan, 1.63 grammes of 

 the sodium combination is given. 



Eau d'Alibour. 



The original formula for this water is 

 in possession of the family Jaussin. to 

 whom it was handed down by the heirs 

 of Dr. Alibour, a physician practicing at 



the court of Henry the Fourth. In 

 ScJnvek. Apoth.-Ztg, 191 5, 638, the fol- 

 lowing formula for this water is given : 

 Exsiccated ferrous sulphate, 61.18 

 grammes, copper sulphate, 15.29 

 grammes, saffron. 3.82 grammes, cam- 

 phor. 3.82 grammes, and water 2 

 kilogrammes. 



Preparation of Acetom Sabadillae. 



Joltze, in F/iarm. Ztg. 1915, 823 calls 

 attention to the difficulties experienced in 

 filtering this preparation when made in 

 the customary manner. He suggests that 

 the plant part be macerated in diluted 

 acetic acid for a period of from 8 to 10 

 days, and not with the customary mix- 

 ture of diluted acetic acid and alcohol. 

 After filtration and expression 2 and 3 

 grammes of dried albumen for each 5 

 liters of liquid are added, and the liquid 

 heated. The albumen acts as a clarify- 

 ing agent, and after subsequent filtration, 

 the alcohol is added. 



Aurocantan 



It is stated that this compound has 

 proven to be of considerable value in 

 the treatment of tuberculosis. Chemically 

 it is cantharidyl-aethylen-diamino-auro- 

 cyanide. It is obtained by interaction 

 between gold cyanide, cantharidin and 

 ethylene-di-amine. S])iess and Feldt, in 

 Aerztl. Rundschau, 191 5, No. 37, give a 

 detailed account of the action of this 

 compound. They claim that its action 

 upon the kidneys is 600 times less toxic 

 than that of cantharidin. The compound 

 is marketed in the ampulle form, con- 

 taining from I to 2 mils of a 2.50% solu- 

 tion. The best results were obtained by 

 injection directlv into the veins. 



