Cbc 



journal of Pbarniacology, 



Devoted to the Advances Made in Materia Medica in its Branches. 



Pharmacy, Pharmacognosy, Chemistry, Botany, Pharmaco- 



Dynamics, Therapeutics and Toxicology* 



Published for the Alumni Association of the College of Pharmacy of the City of New York, 

 by The New Era Printing Company, 41 North Queen St., Lancaster, Pa. 



Vol.. VII. NIAY, 1900. No. 5. 



Urine Analysis by the Pharmacist. ubviah^' 



• NEW 'i 



By George C. Diekman, Ph.G., M.D. ^^ 



(Continued from April Number.) 

 PART THIRTEEN. 



Phosphates (H3PO4 — P2O5). 



Phosphoric acid is found in urine combined with the alkalies, sodium, 

 potassium and ammonium (Alkali Phosphates), and with the alkali 

 earths, calcium and magnesium (Earthy Phosphates). In normal acid 

 urine about 60 per cent, of the total phosphoric acid is present in the form 

 of a di-hydric salt (XH2PO4), and about 40 per cent, in the form of 

 mono-hydric (X 2HPO4) and normal salts (X 3 PO4). A somewhat vari- 

 able, but always small, quantity of phosphoric acid may be present in 

 the form of Glycerin Phosphoric Acid or in combination with neurin, as 

 lecithin. 



The avearge quantity of phosphoric acid, expressed as PoOs, excreted 

 in the urine of an adult during twenty-four hours amounts to about 3.5 

 grammes. Of this quantity two-thirds is in combination with the alkalies, 

 and one-third with the alkali earths. Such quantities are, however, sub- 

 ject to considerable variation, even in the healthy individual. 



The chief sources of phosphoric acid are as follows : 



A. From phosphates taken in as such, with the food. 



B. From the oxidation of certain organic bodies, such as lecithin, 

 nuclein, etc., which may form part of the food taken in. 



