Cbe 



journal of Pharmacology, 



Devoted to the Advances Made in Materia Medica in its Branches. 



Pharmacy, Pharmacognosy, Chemistry, Botany, Pharmaco- 



Dynamics, Therapeutics and Toxicology. 



Published for the Alumni Association of the College of Pharmacy of the City of New York, 

 by The New Era Printing Company, 41 North Queen St., Lancaster, Pa. 



Vol.. vir. 



APRIL., 1900. 



No. 4. 



Urine Analysis by the Pharmacist. 



By George C Diekman, Ph.G., M.D, 



LIBRARY 

 NEW YORK 

 BOTANICAL 



GARDEN. 



(Continued from February Number.) 



PART TWBlvVE. 



Sulphuric Acid. — Continued. 

 I. Quantitative Estimation of Sulphuric Acid (Gravimetric). 



In the estimation of sulphates, both forms which occur in urine must be 

 considered. The separation and estimation of the two forms of sulphates 

 may be readily accomphshed by the method of Baumann. The simple or 

 praeformed sulphates are precipitated upon the addition of barium chloride 

 solution, after first acidifying with acetic acid, a minimum quanthy of acid 

 being employed, ethereal or conjugate sulphates remain in solution. The 

 latter are precipitated after boiling with mineral acids, and adding barium, 

 chloride. 



A. Simple or praeformed sulphates. 



50-100 cubic centimeters of filtered urine are diluted with an equal vol- 

 ume of water, and acidified with acetic acid. An excess of barium chloride 

 solution is added, and the whole warmed on a water bath until the precipi- 

 tate which has formed, becomes granular. From one-half to one hour will be 

 required. Set aside for a few hours and then filter, through an ashless- 

 filter reserving the filtrate. Wash the precipitate until free from chlorides, 

 using hot water. Dry, and transfer to a tared platinum crucible and ignite. 

 It happens at times that the precipitate of barium sulphates carries dowrt 



