244 



THE JOURNAIv OF PHARMACOLOGY. 



plantations, with Fig. 2, showing typical commercial Bolivian leaves. 

 The former are larger, thinner, and paler, and the lateral lines are usually 

 exaggerated. I assume that this is the character of a specimen collected 

 by Holton in 1853 in New Granada (Fig. 7), and that its long and slender 

 pedicels may be due to the same condition. This specimen is classed in 

 the Kew Herbarium under E. popayanneiisis Poepp. With these I class 

 Fig. 8, collected by myself near the geographical center of South America, 

 many hundred of miles from any plantation, and Fig. 9, which I collected 

 near the mouth of the Orinoco. This drawing does not sufiiciently empha- 



FiG. 6. Wild, shade-grown coca leaves. 



Fig. 8. Erythroxylon Popayannesis 

 Poepp. Eastern Bolivia ; 

 not cultivated. 



size the presence of the areola, though there are no distinct collenchyma 

 lines. Although not the province of this paper to discuss the relations of 

 species proposed subsequently to the publication of E. coca with that 

 species, I may in passing call attention to the extremely close relationship 

 between these forest-grown specimens of E. coca and E. popayannensis. 

 It appears not in the least unlikely that the latter species is really nothing 

 but the former. 



Similarly, the closeness of E. angtiifiigum (Fig, 10) to the ovate-acum- 

 inate wild E. coca is apparent. It was for a long time questionable with 

 me whether these two were not specifically identical, but the different 

 secondary veins and, above all, the highly inequilateral tapering fruits of 

 the former, forbid. 



( To be continued.) 



