with morphogenesis and protein synthesis in the absence of the nucleus. Two 

 contributions by Beermann discuss "puffing" in Dipteran giant chromosomes, 

 and lampbrush Y chromosomes in Drosophila spermatocytes. A brief paper by 

 Monroy deals with genetic control of gastrulation in echinoderms. Turpin then 

 deals with heterocaryotic monozygotic twins in man, while Jerome extensively 

 discusses recent evidence correlating quantitative and qualitative modifications 

 of protein metabolism with certain human chromosome aberrations, evidence 

 obtained in part on in vitro cultures. Finally, Turchini deals with recent research 

 on enzyme histochemistry in the chick embryo, and particularly on enzyme 

 transfer during inductive processes. 



The book is adequately illustrated and is concluded by an index to authors. 



46 GROWTH OF THE NERVOUS SYSTEM 



1968 



Editors: G. E. W. Wolstenholme and J. & A. Churchill Ltd. 



M. O'Connor London 



A Ciba Foundation Symposium 

 306 pp., 101 figs., 5 tbs. 



Participants: Buller (Bristol), Grain (New York), Drachman (Boston, Mass.), Eayrs (London), 

 Eccles (Chicago, 111.), Gaze (Edinburgh), Gutmann (Prague), Hamburger (St. Louis, Mo.), Hnik 

 (Prague), Hughes (Bristol), Kerkut (Southampton), Kollros (Iowa City, Iowa), Levi-Montalcini 

 (St. Louis, Mo.), Mugnaini (Oslo), Muntz (Bristol), Murray (New York), Piatt (Philadelphia, 

 Pa.), Prestige (Bristol), Singer (Cleveland, Ohio), Sperry (Pasadena, Calif.), StefanelU (Roma), 

 Szekely (Pecs), Szentagothai (Budapest), Walton (Newcastle), Whittaker (Cambridge), Young 

 (London) 



This book contains the proceedings of a three-day Symposium held in London 

 in June 1 967. It was attended by 26 participants, the majority of whom came from 

 England and the U.S.A., while two each came from Czechoslovakia and Hun- 

 gary respectively. 



There is an introductory survey of the field by J. Szentagothai, followed by 

 13 research papers divided among four sessions: L Development of specific neur- 

 onal connexions (4); IL Development of movement (2); IIL Role of chemically 

 specific signals in the development of the nervous system (3); IV. Trophic inter- 

 action, peripheral and central (4). Almost all papers in the first three sessions are 

 of interest to developmental biologists generally. The fourth session is of specific 

 interest to neurobiologists only. 



Session I contains papers on interneuronal connexions in vitro (mammals; 

 Grain et al), on retino-tectal connexions (Sperry and Hibbard), on the effects 

 on brain and retina of optic nerve lesions (Gaze and Watson), and on the de- 

 velopment of limb movements (Szekely) (the latter three in amphibians) . Session 

 II contains a paper on early co-ordinated movements in the chick embryo (Ham- 

 burger) and one on the development of limb innervation (Hughes). The papers 

 in session III report on work carried out with the "nerve growth factor" from 

 mouse salivary glands (Levi-Montalcini and Angeletti), with the deuterium 

 isotope (Murray and Benitez), and with various hormones (Kollros). 



The discussions held at the Symposium are recorded in full and contain a 

 wealth of additional information, complete with literature references. 



The book is well illustrated and has a subject index and an index to lecturers 

 and contributors to the discussions. 



39 



