from patients manifesting biochemical defects. The preface by the Symposium 

 organizer, M. N. Goldstein, is an annotated summary of the whole Symposium. 



The book is beautifully produced and profusely illustrated. The reproduction 

 of the numerous photographs is superb. The book is concluded by a subject index. 



44 SECOND DECENNIAL REVIEW CONFERENCE 



ON CELL TISSUE AND ORGAN CULTURE 

 1967 



Editor: B. B. Westfall Natl. Cancer Institute 

 Natl. Cancer Institute Bethesda, Md. 



Monograph 26 Price: $ 4. — 



442 pp., 56 figs., 61 pis., 17 tbs. 



Contributors: Abercrombie (London), Amos (Boston, Mass.), Bell (Cambridge, Mass.), 

 DeMars (Madison, Wis.), Fames (Providence, R.I.), Gartler (Seattle, Wash.), Grobstein (La 

 Jolla, Calif.), Hayflick (Philadelphia, Pa.), Herrmann (Storrs, Conn.), Pitot (Madison, Wis.), 

 Sanford (Bethesda, Md.), Sutton (Baltimore, Md.), Waymouth (Bar Harbor, Maine), Westfall 

 (Bethesda, Md.) 



The central theme of this 5-day Conference, held in Bedford, Pa. in September 

 1966, was the relationship between the cultured cell or tissue and its in vivo 

 progenitor. The Conference was in seven sessions of two papers each. Each 

 session had a panel of usually three distinguished specialists. The lengthy dis- 

 cussions between the lecturers, the panel members, and members of the large 

 audience are recorded in full. 



Problems of differentiation, dedifferentiation, and phenotypic stability of 

 cells in culture crop up in almost every session. However, of the 14 papers only 

 five will be singled out here for their direct interest to developmental biologists. 

 They are the papers by Bell on control of synthetic activity in differentiating 

 cells, by Sutton on ultrastructural aspects of monocyte development, by Aber- 

 crombie on contact inhibition, by Grobstein on mechanisms of organogenetic 

 tissue interaction, and by Herrmann et al. on growth rate and differentiated 

 function of cells. Apart from the second, all these papers are synthetic in nature, 

 and all have extensive bibliographies. 



The book is adequately illustrated and remarkably cheap. It has no indexes. 



45 DE L'EMBRYOLOGIE EXPERIMENTALE 



A LA BIOLOGIE MOLECULAIRE 

 1967 



Editor: E. Wolff Dunod 



174 pp., 53 figs., 13 tbs. Paris 



(paper-bound) Price: F 32 



Contributors: Beermann (Tubingen), Brachet (Bruxelles), Jerome (Paris), Monroy (Palermo), 

 Turchini (Montpellier), Turpin (Paris). 



This rather heterogeneous and expensive collection of papers is based on a 

 series of seminars given at the College de France during 1965 and 1966. 



A brief introduction by Wolff is followed by two papers by Brachet, one 

 dealing with the role of the nucleus and nucleic acids in morphogenesis, the other 



38 



