The book consists of ten chapters, each of which embodies an authoritative 

 paper as well as a "demonstration". The latter usually consists of a concise 

 text supplemented with ample illustrations, pertaining to techniques and proce- 

 dures used in, or devised for teratogenetic work and the evaluation of its 

 results. This material includes representative photographs of sectioned, cleared 

 or dissected material, specimens of protocol sheets, chronological tables, etc. 

 etc. The demonstrations do not always bear a strict relation to the preceding 

 paper. 



The authors are distinguished authorities from the U.S.A. (9) and Canada 

 (2). Except for the first paper, which is a historical synopsis, all chapters 

 contain hitherto unpublished research material, both on mammals and the 

 chick. The papers cover a broad range of subjects such as embryological and 

 genetic aspects of teratology, interaction of intrinsic and extrinsic factors, 

 nutritional factors, drug response factors, growth inhibitors, immunological 

 aspects. Techniques to which special attention is devoted include breeding and 

 maintenance of rats and mice, transplantation of mammalian ova, chick embryo 

 explantation and yolk sac perfusion, uterine vascular clamping, differential 

 irradiation, immunological methods, electrophoretic methods, and methods of 

 administering teratogenetic agents. 



The book is very well printed and profusely illustrated. There are no 

 indexes. 



On account of the highly diverse nature of the subject matter and of its haphazard arran- 

 gement in the book (a consequence of the character of a Workshop) it is highly regrettable 

 that no alphabetical index is included. An author index would also have been useful. The 

 reproduction of photographic illustrative material is not always entirely satisfactory. 



Participants: Brent (Philadelphia, Pa.), Eraser (Montreal), Johnson (Gainesville, Fla.), 

 Kalter (Cincinnati, Ohio), Karnofsky (New York, N.Y.), Klein (Milwaukee, Wise), Murphy 

 (New York, N.Y.), Runner (Boulder, Colo.), Trasler (Montreal), Warkany (Cincinnati, Ohio), 

 Wilson (Gainesville, Fla.). 



34. NEW METHODS IN EMBRYOLOGY 



Detection of molecules through immunochemical methods 

 1965 



Editor: Et. Wolff Hermann 



Actualites Scientifiques et Industrielles 1321 Paris 



231 pp., 85 figs., 18 tbs. 

 (paper-bound) 



This book is the outcome of a series of seminars organized in 1964 by Prof. 

 Et. Wolff at the College de France, Paris. Speakers in these seminars were 

 four well-'known European specialists in chemical embryology (Ranzi, ten 

 Gate f, van Doorenmaalen, Croisille), and a well-known imraunochemist, 

 originator of the immuno-electrophoretic technique (Grabar, of the Institut 

 Pasteur). 



The book contains an introduction by Et. Wolff, a general paper by Grabar 

 on immunochemical studies of cell and tissue constituents, and five extensive 

 papers on more specific subjects, ranging in size from 24 to 74 pages. The 

 papers by ten Gate and by van Doorenmaalen are in English, while all the other 

 contributions are in French. 



The titles of the five special papers are as follows: "Problemes d'immuno- 

 chimie et de la differenciation proteique dans le developpement des oursins, 



352 



