des batraciens et d'autres animaux" (Ranzi); "Considerations on the problem 

 of differentiation and a review of immunochemical studies on the embryonic 

 brain and ocular lens" (ten Gate); "Immunohistological studies of proteins 

 during the development of chick lens" (van Doorenmaalen); "Synthese et 

 distribution des proteines contractiles, myosine et actine, pendant le developpe- 

 ment des muscles cardiaque et squelettique chez I'embryon de poulet" (Croisil- 

 le); "Etude, par les methodes immunochimiques, de I'apparition de quelques 

 constituants caracteristiques du foie et du rein adultes pendant le developpe- 

 ment embryonnaire du poulet" (Croisille). 



The book is printed in photo-offset; the photographical illustrations are well- 

 printed on glossy paper. The book has no index. 



The main title of the book suggests that it is the first of a series of similar books. However, 

 this is not explicitly stated, and if it should not be so, the choice of the main title is unfor- 

 tunate, because it suggests a much wider scope than is actually offered. 



35. RETENTION OF FUNCTIONAL DIFFERENTIATION 

 IN CULTURED CELLS 

 1964 



Editor: V. Defendi The Wistar Institute Press 



The Wistar Institute Symp. Monographs, nr. 1 Philadelphia 



127 pp., 32 figs., 6 pis., 15 tbs. Price: $ 5.— 



(paper-bound) 



This is a report of a symposium held at the Wistar Institute, Philadelphia, 

 March 1964. It was the first of a series of one-day symposia to be held at the 

 Wistar Institute each year in early spring, and to be published in the same 

 year. Each symposium will deal with a relatively well-defined field of inves- 

 tigation which is still in an initial phase, but rapidly expanding. 



The present symposium had 45 participants, all but one from the U.S.A. Ten 

 papers were read, ranging in length from 6-18 pages. The first paper, "Con- 

 tinued inductive tissue interaction during differentiation of mouse embryonic 

 rudiments in vitro", by Auerbach deals with organ culture rather than cell 

 culture. All other papers are concerned with cultured vertebrate (mostly 

 mammalian) cells. All papers report on original research, mostly with stress on 

 biochemistry and immunology. Papers of specific interest to developmental 

 biologists are those by Cooper and Lash ("Embryonic cell cultures and in- 

 herent obsolescence") and by Davidson ("Gene activity in differentiated 

 cells"). 



All papers are followed by discussions. The book is well-illustrated. It has 

 an author index and a brief subject index. 



The subject index is based on titles of papers only, and hence its usefulness is almost nil. 



Participants: Ambrose (Boston, Mass.), Auerbach (Madison, Wis.), Beam (New York, 

 N.Y.), Bennett (Rye, N.Y.), Billingham (Philadelphia, Pa.). Boyse (Rye, N.Y.), Buonassisi 

 (Waltham, Mass.), Coon (Waltham, Mass.), Cooper (Philadelphia, Pa.), Davidson (New 

 York, N.Y.), Dawe (Bethesda, Md.), Defendi (Philadelphia, Pa.). De Mars (Madison, Wis.), 

 Eagle (New York, N.Y.), Earle (Bethesda, Md.). Ephrussi (Cleveland, Ohio). Flexner 

 (PhUadelphia, Pa.), Gartler (Seattle, Wash.), Gey (Baltimore, Md.), Goldstein (Memphis, 

 Tenn.), Grant (Washington, D.C.), Green (New York, N.Y.), Hayflick (Philadelphia, Pa.), 

 Holtzer (Philadelphia, Pa.), Hungerford (Fox Chase, Pa.). Konigsberg (Baltimore, Md.), 

 Koprowska (Philadelphia, Pa.), Koprowski (Philadelphia, Pa.), Krooth (Ann Arbor, Mich.), 

 Lash (Philadelphia, Pa.), Love (Philadelphia, Pa.), Markert (Baltimore, Md.). Moorhead 

 (Philadelphia, Pa.), Myers (Pittsburg, Pa.), NoweU (PhUadelphia. Pa,). Old (Rye, N.Y.), 



353 



