G. Dclgado Palacios 



8i 



reliable methods/ it is found that these substances present parallel 

 variations, and that the proportions of soluble calcium and volatile 

 fatty acids are greater in calcariuric patients than in normal persons. 

 Similar variations, though greater, are observed in diabetics, who, I 

 believe, suffer from calcariuria and lipaciduria, sometimes with the 

 greatest intensity. In the urine of all these persons the quan- 

 tities of calcium and volatile fatty acids show correlative variations. 

 Some of the figures obtained in these connections, for normal and 

 calcariuric persons, are appended. 



Volume cc. 



Calcium 

 CaO gm. 



B.deT... 

 A. C 



24 hour urine. 

 24 hour urine . 



973 

 1231 



0.312 

 0.224 



F. W. 

 L. C. 



24 hour urine. 

 24 hour urine . 



Volume cc. 



3.202 

 1-939 



Calcium 

 CaO gm. 



0.576 

 0.512 



These analytic results are fundamentally opposed to Soetbeer's 

 assumption that the diminished quantity of fecal calcium in such pa- 

 tients is due to special Colitis, which impedes the excretion of ab- 

 sorbed calcium, the latter being eliminated compensatorily by the 

 kidney. From the analytic data above, it may be observed that in 

 the patients in which the total intestinal excretion of calcium ought 

 to be impeded and least, the Proportion of fecal soluble-calciimi is 

 greatest. 



1 Calcium was quantitatively estimated by the Neubauer-Huppert method 

 (14), slightly modified, and volatile fatty acids by the Schmidt and Strasburger 

 method (15). 



