14 



THE NEW YORK JOURNAL OF PHARMACY 



Suppose 50 grammes of fruit juice 

 had been employed. 10 ccm of the 

 petroleum ether layer produced with 

 the solution of iron chloride, a violet 

 color, corresponding with a "Compari- 

 son" solution in the preparation of 

 which 2,5 ccm of the petroleum ether 

 layer were employed. Then : 



5 • c 5 . 2.5 



X — = = 0.025, 



a . b 50 . 10 

 The preparation therefore contains 

 0,025 per cent, of Salicylic Acid. 



If the methods to be used in the 

 cases of liquids containing alcohol, this 

 must first be removed, as otherwise 

 the relation of 2 to i of the petroleum 

 ether and alcohol, necessary for a prop- 

 er extraction, would be destroyed. 



Melting Point of Mixtures of Cacao 

 Butter and Yellow Wax. 



J. van Biel and P. van der Wielen, 

 in Pharm. Weekb., have made the fol- 

 lowing observations: Mixtures of 

 Cacao Butter with 3.00% of Yellow 



Wax = M. P. 31.2° 

 Cacao Butter with 4.05% of Yellow 



Wax = M. P. 32.6° 

 Cacao Butter with 4.80% of Yellow 



Wax = M. P. 34.8° 

 Cacao Butter with 6.05% of Yellow 



Wax = M. P. 37° 

 Cacao Butter with 7.00% of Yellow 



Wax = M. P. 38.2° 

 Mixtures of this kind should not pos- 

 sess a melting point above yj° C, the 

 body temperature, about 5 per cent, of 

 yellow wax should be the limit. The 

 authors also found that aqueous solu- 

 tion can readily be ^incorporated in 

 such mixtures. Thus to 2 g'rammes of 

 a mixture of cacao butter with 2j^% 

 of yellow wax, i gramme of an aqueous 



solution, glycerine or ichthyol may be 

 added with ease. 



Constituents of Ipe Tabaco Wood. 



O. A. Oesterle, in Schweiz. Wochen- 

 schr. f. Chem. u. Pharm., states the 

 following: A fluid extract as well as 

 a tincture of this wood are found 

 ready made in all Brazilian pharma- 

 cies. Aqueous infusions of the wood 

 are employed in certain skin diseases. 

 The wood is also employed in build- 

 ing operations, and contains a color- 

 ing matter used in dyeing cotton fab- 

 rics. 



Peckolt found that the wood con- 

 tained a resin which does not resemble 

 the resin found in guaiac wood in the 

 least. He also found that this wood 

 contains a considerable quantity of a 

 yellow substance, which he states is 

 identical with chrysophanic acid. Th. 

 E. Lee, who examined this wood rel- 

 ative to its coloring matter, also re- 

 ports the presence of a 5'ellow sub- 

 stance, useful in dyeing, and which he 

 called Tecomin. 



According to the investigations of 

 the author this yellow substance 

 crystallizes from hot alcoholic solu- 

 tions in flat yellow needles or plates, 

 which after repeated crystallization 

 melt at 142-143° C. The substance dis- 

 solves readily in most organic solvents. 

 Its solution is alkalies and alkali car- 

 bonates are colored an intensive red. 

 In sulphuric acid it dissolves with a 

 yellowish-red color. If the solution in 

 alkalies is boiled with zinc dust, it be- 

 comes decolorized. In glacial acetic 

 acid it dissolves with an orange-red 

 color, which disappears upon treatment 

 with zinc and h3^drochloric acid. Tl^ 

 decolorized solutions when exposed to 



